Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

Kathryn J. Lindley; Amanda K. Verma; Lori A. Blauwet

doi:10.1016/j.hfc.2018.08.004

Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

Kathryn J. Lindley
, Amanda K. Verma
, Lori A. Blauwet

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

Original language	English
Pages (from-to)	29-39
Number of pages	11
Journal	Heart Failure Clinics
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.hfc.2018.08.004
State	Published - Jan 2019

Keywords

Diagnosis
Heart failure
Peripartum cardiomyopathy
Pregnancy
Prognosis

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10.1016/j.hfc.2018.08.004

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title = "Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis",

abstract = "Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45\% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.",

keywords = "Diagnosis, Heart failure, Peripartum cardiomyopathy, Pregnancy, Prognosis",

author = "Lindley, \{Kathryn J.\} and Verma, \{Amanda K.\} and Blauwet, \{Lori A.\}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",

year = "2019",

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doi = "10.1016/j.hfc.2018.08.004",

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T2 - Progress in Understanding the Etiology, Management, and Prognosis

AU - Lindley, Kathryn J.

AU - Verma, Amanda K.

AU - Blauwet, Lori A.

PY - 2019/1

Y1 - 2019/1

N2 - Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

AB - Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

KW - Diagnosis

KW - Heart failure

KW - Peripartum cardiomyopathy

KW - Pregnancy

KW - Prognosis

UR - https://www.scopus.com/pages/publications/85055571785

U2 - 10.1016/j.hfc.2018.08.004

DO - 10.1016/j.hfc.2018.08.004

M3 - Review article

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AN - SCOPUS:85055571785

SN - 1551-7136

VL - 15

SP - 29

EP - 39

JO - Heart Failure Clinics

JF - Heart Failure Clinics

IS - 1

ER -

Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

Abstract

Keywords

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