Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

Kathryn J. Lindley; Amanda K. Verma; Lori A. Blauwet

doi:10.1016/j.hfc.2018.08.004

Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

Kathryn J. Lindley, Amanda K. Verma, Lori A. Blauwet

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

Original language	English
Pages (from-to)	29-39
Number of pages	11
Journal	Heart Failure Clinics
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.hfc.2018.08.004
State	Published - Jan 2019

Keywords

Diagnosis
Heart failure
Peripartum cardiomyopathy
Pregnancy
Prognosis

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10.1016/j.hfc.2018.08.004

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title = "Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis",

abstract = "Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.",

keywords = "Diagnosis, Heart failure, Peripartum cardiomyopathy, Pregnancy, Prognosis",

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PY - 2019/1

Y1 - 2019/1

N2 - Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

AB - Occurring in approximately 1 in 1000 live births in the United States, peripartum cardiomyopathy (PPCM) is characterized by left ventricular ejection fraction reduced to less than 45% near the end of pregnancy or within the first 5 months after delivery. Although the cause of PPCM remains unclear, increasing evidence supports a complex interaction of genetic and environmental factors contributing to angiogenic imbalance, which may lead to myocardial dysfunction in a susceptible woman. This article reviews the progress that has been made regarding understanding of the cause, management, and natural history of PPCM.

KW - Diagnosis

KW - Heart failure

KW - Peripartum cardiomyopathy

KW - Pregnancy

KW - Prognosis

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Peripartum Cardiomyopathy: Progress in Understanding the Etiology, Management, and Prognosis

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Keywords

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