Performance evaluation of the microPET®-Focus - F120

Richard Laforest, Desmond Longford, Stefan Siegel, Danny F. Newport, Jeffrey Yap

Research output: Contribution to journalConference article

20 Scopus citations

Abstract

microPET®-Focus-F120 is the latest model of dedicated small animal PET scanners from CTI-Concorde Microsystems LLC, (Knoxville, TN). This scanner, based on the geometry of the microPET-R4, takes advantage of several system design changes and modifications to the coincidence processing electronics that improve the image resolution, sensitivity, and counting rate performance as compared to the predecessor models. This work evaluates the performance of the Focus-F120 system and shows its improvement over the earlier models. In particular, the spatial resolution has been shown to improve from 2.20 to 1.75 mm at 0.5mm radial distance, the peak absolute sensitivity to increase from 4.1% to 7.1% in comparison to the microPET-R4. The counting rate capability, expressed in NECR, was shown to peak at over 800 kcps at 88 MBq, while the microPET-R4 peak is reached at 167 MBq, in a mouse phantom. For this small phantom, the NECR counting rate is limited by the data transmission bandwidth between the scanner and the acquisition console. Evaluation of image quality and quantitation accuracy was also performed using specially designed phantoms and animal experiments.

Original languageEnglish
Article numberM5-118
Pages (from-to)2965-2969
Number of pages5
JournalIEEE Nuclear Science Symposium Conference Record
Volume5
StatePublished - Dec 1 2004
Event2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy
Duration: Oct 16 2004Oct 22 2004

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    Laforest, R., Longford, D., Siegel, S., Newport, D. F., & Yap, J. (2004). Performance evaluation of the microPET®-Focus - F120. IEEE Nuclear Science Symposium Conference Record, 5, 2965-2969. [M5-118].