Penicilliosis.

Penicillium marneffei (PM) is a fungal pathogen that has become a common cause of opportunistic infection in HIV-infected patients in Southeast Asia and Southern China. Clinical features usually present as disseminated infection, reminiscent of disseminated infection with other endemic mycoses or of disseminated mycobacterial infection. Common symptoms involve fever, anemia, and weight loss. Clinical features of children with PM in HIV infection are identical to those seen in adults. Amphotericin B has become standard therapy followed by itraconazole once clinical resolution has been achieved.