PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin

Shayla Shmuel; Sébastien Monette; Dina Ibrahim; Patrícia M.R. Pereira

doi:10.1007/s11307-024-01917-x

PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin

Shayla Shmuel
, Sébastien Monette
, Dina Ibrahim
, Patrícia M.R. Pereira

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.

Original language	English
Pages (from-to)	569-576
Number of pages	8
Journal	Molecular Imaging and Biology
Volume	26
Issue number	4
DOIs	https://doi.org/10.1007/s11307-024-01917-x
State	Published - Aug 2024

Keywords

EBV
PDXs
Theranostics

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10.1007/s11307-024-01917-x

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abstract = "This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.",

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AU - Shmuel, Shayla

AU - Monette, Sébastien

AU - Ibrahim, Dina

AU - Pereira, Patrícia M.R.

N1 - Publisher Copyright: © The Author(s), under exclusive licence to World Molecular Imaging Society 2024.

PY - 2024/8

Y1 - 2024/8

N2 - This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.

AB - This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.

KW - EBV

KW - PDXs

KW - Theranostics

UR - https://www.scopus.com/pages/publications/85191048209

U2 - 10.1007/s11307-024-01917-x

DO - 10.1007/s11307-024-01917-x

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ER -

PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin

Abstract

Keywords

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