TY - JOUR
T1 - PBM competition in pharmaceutical supply chain
T2 - Formulary design and drug pricing
AU - Kouvelis, Panos
AU - Xiao, Yixuan
AU - Nan, Yang
N1 - Publisher Copyright:
© 2015 INFORMS.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - We model the competition among multiple pharmacy benefit managers (PBMs) for the patronage of a client organization. Each PBM selects a list of prices to be charged to the client organization for each of the branded and generic drugs within a therapeutic class (price decision) and a formulary list that assigns branded drugs to preferred or nonpreferred tiers (formulary decision). Drug manufacturers offer rebates to PBMs for drugs on preferred tier of formularies. The individuals participating in the client’s pharmacy benefit plan are the ones consuming the drugs and making purchasing decisions, whereas the client organization is paying the majority of drug cost. The choices of the individuals and the client organization are governed by different utility measures. For this complex drug distribution setting and for competing PBMs, we show the existence and uniqueness of a pure Nash equilibrium on aggregate formulary and price decisions, which represent the welfare-adjusted cost and welfare-adjusted price of each PBM’s plan, respectively. We characterize each PBM’s optimal formulary and equilibrium price decisions and discuss the impact of various model primitives. We apply our model to gain insights on the impact of mergers in the PBM industry.
AB - We model the competition among multiple pharmacy benefit managers (PBMs) for the patronage of a client organization. Each PBM selects a list of prices to be charged to the client organization for each of the branded and generic drugs within a therapeutic class (price decision) and a formulary list that assigns branded drugs to preferred or nonpreferred tiers (formulary decision). Drug manufacturers offer rebates to PBMs for drugs on preferred tier of formularies. The individuals participating in the client’s pharmacy benefit plan are the ones consuming the drugs and making purchasing decisions, whereas the client organization is paying the majority of drug cost. The choices of the individuals and the client organization are governed by different utility measures. For this complex drug distribution setting and for competing PBMs, we show the existence and uniqueness of a pure Nash equilibrium on aggregate formulary and price decisions, which represent the welfare-adjusted cost and welfare-adjusted price of each PBM’s plan, respectively. We characterize each PBM’s optimal formulary and equilibrium price decisions and discuss the impact of various model primitives. We apply our model to gain insights on the impact of mergers in the PBM industry.
KW - Competition
KW - Drug distribution
KW - Pharmacy benefit manager
KW - Pricing
KW - Tiered-formulary
UR - https://www.scopus.com/pages/publications/84946730320
U2 - 10.1287/msom.2015.0542
DO - 10.1287/msom.2015.0542
M3 - Article
AN - SCOPUS:84946730320
SN - 1523-4614
VL - 17
SP - 511
EP - 526
JO - Manufacturing and Service Operations Management
JF - Manufacturing and Service Operations Management
IS - 4
ER -