Patients with uncontrolled components of metabolic syndrome have increased risk of complications following total joint arthroplasty

Benjamin Zmistowski, Ismar Dizdarevic, Christina L. Jacovides, Kris E. Radcliff, Boris Mraovic, Javad Parvizi

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Metabolic syndrome (MetS)-a diagnostic grouping of diabetes, dyslipidemia, hypertension, and obesity-has been indicated as a risk factor for perioperative complications following total joint arthroplasty (TJA). This study investigates the impact of MetS on perioperative complications, specifically the importance of controlling MetS components. One hundred thirty-three patients undergoing TJA with all four components of MetS were identified. They were matched one-to-one with patients without MetS. Control of diabetes, dyslipidemia, and hypertension was assessed. Thirty-five patients with MetS were found to have at least a single uncontrolled component. The complication rates were 49%, 8%, and 8% for uncontrolled MetS, controlled MetS, and no MetS, respectively. Multivariate analysis confirmed independent associations between control of MetS components and both perioperative complications and length of stay. Both surgeons and patients should be aware of the substantial risk of dangerous complications following TJA in patients with uncontrolled metabolic syndrome.

Original languageEnglish
Pages (from-to)904-907
Number of pages4
JournalJournal of Arthroplasty
Volume28
Issue number6
DOIs
StatePublished - Jun 2013

Keywords

  • Complications
  • Diabetes
  • Dyslipidemia
  • Hypertension
  • Total joint arthroplasty
  • Uncontrolled metabolic syndrome

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