TY - JOUR
T1 - Patients with uncontrolled components of metabolic syndrome have increased risk of complications following total joint arthroplasty
AU - Zmistowski, Benjamin
AU - Dizdarevic, Ismar
AU - Jacovides, Christina L.
AU - Radcliff, Kris E.
AU - Mraovic, Boris
AU - Parvizi, Javad
PY - 2013/6
Y1 - 2013/6
N2 - Metabolic syndrome (MetS)-a diagnostic grouping of diabetes, dyslipidemia, hypertension, and obesity-has been indicated as a risk factor for perioperative complications following total joint arthroplasty (TJA). This study investigates the impact of MetS on perioperative complications, specifically the importance of controlling MetS components. One hundred thirty-three patients undergoing TJA with all four components of MetS were identified. They were matched one-to-one with patients without MetS. Control of diabetes, dyslipidemia, and hypertension was assessed. Thirty-five patients with MetS were found to have at least a single uncontrolled component. The complication rates were 49%, 8%, and 8% for uncontrolled MetS, controlled MetS, and no MetS, respectively. Multivariate analysis confirmed independent associations between control of MetS components and both perioperative complications and length of stay. Both surgeons and patients should be aware of the substantial risk of dangerous complications following TJA in patients with uncontrolled metabolic syndrome.
AB - Metabolic syndrome (MetS)-a diagnostic grouping of diabetes, dyslipidemia, hypertension, and obesity-has been indicated as a risk factor for perioperative complications following total joint arthroplasty (TJA). This study investigates the impact of MetS on perioperative complications, specifically the importance of controlling MetS components. One hundred thirty-three patients undergoing TJA with all four components of MetS were identified. They were matched one-to-one with patients without MetS. Control of diabetes, dyslipidemia, and hypertension was assessed. Thirty-five patients with MetS were found to have at least a single uncontrolled component. The complication rates were 49%, 8%, and 8% for uncontrolled MetS, controlled MetS, and no MetS, respectively. Multivariate analysis confirmed independent associations between control of MetS components and both perioperative complications and length of stay. Both surgeons and patients should be aware of the substantial risk of dangerous complications following TJA in patients with uncontrolled metabolic syndrome.
KW - Complications
KW - Diabetes
KW - Dyslipidemia
KW - Hypertension
KW - Total joint arthroplasty
KW - Uncontrolled metabolic syndrome
UR - http://www.scopus.com/inward/record.url?scp=84878199227&partnerID=8YFLogxK
U2 - 10.1016/j.arth.2012.12.018
DO - 10.1016/j.arth.2012.12.018
M3 - Article
C2 - 23522489
AN - SCOPUS:84878199227
SN - 0883-5403
VL - 28
SP - 904
EP - 907
JO - Journal of Arthroplasty
JF - Journal of Arthroplasty
IS - 6
ER -