Abstract
We report a patient with hydrocephalus who developed levodopa responsive parkinsonism and severe bradyphrenia associated with shunt malfunction and revision. Magnetic resonance imaging revealed periaqueductal edema involving medial substantia nigra. [18F]dopa positron emission tomography demonstrated reduced uptake in the caudate and putamen with relative sparing of the posterior putamen. Hydrocephalus associated with shunt malfunction can cause a distinct parkinsonian syndrome with greater dysfunction of projections from the medial substantia nigra to anterior striatum than in idiopathic Parkinson's disease.
Original language | English |
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Pages (from-to) | 1617-1619 |
Number of pages | 3 |
Journal | Journal of Neurology, Neurosurgery and Psychiatry |
Volume | 75 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2004 |