Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System

Keyphrases

• Pathologic 100%
• Shear Rate 100%
• ADAMTS13 100%
• Von Willebrand Factor 100%
• Elongation Rate 100%
• Von Willebrand Disease 50%
• Severe Aortic Stenosis 33%
• Exposure Time 33%
• Protease 16%
• Physiological Level 16%
• Aortic Valve 16%
• Aortic Stenosis 16%
• Microfluidic Device 16%
• Metalloproteinases 16%
• Computational Fluid Dynamics 16%
• Aortic Valve Replacement 16%
• Disintegrin 16%
• Severe Stenosis 16%
• Thrombospondin-1 (TSP-1) 16%
• Mild Stenosis 16%
• Computational Fluid Dynamics Simulation 16%
• Member 13 16%
• Mucocutaneous Bleeding 16%
• Microfluidic Design 16%
• Echography 16%
• Main Protease 16%
• Flow Behavior 16%
• Valve Model 16%
• Flow Features 16%
• High Shear 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Von Willebrand Factor 100%
• Von Willebrand Factor Cleaving Proteinase 100%
• Syndrome 71%
• Aortic Stenosis 42%
• Proteinase 28%
• Bleeding 14%
• Metalloproteinase 14%
• Disintegrin 14%
• Stenosis 14%
• Thrombospondin 14%