Pathogen-Negative Sepsis-An Opportunity for Antimicrobial Stewardship

Gabriel C. Lockhart; Jacob Hanin; Scott T. Micek; Marin H. Kollef

doi:10.1093/ofid/ofz397

Pathogen-Negative Sepsis-An Opportunity for Antimicrobial Stewardship

Gabriel C. Lockhart
, Jacob Hanin
, Scott T. Micek
, Marin H. Kollef

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4-9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.

Original language	English
Article number	ofz397
Journal	Open Forum Infectious Diseases
Volume	6
Issue number	10
DOIs	https://doi.org/10.1093/ofid/ofz397
State	Published - Oct 1 2019

Keywords

pathogen-negative
sepsis
stewardship

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10.1093/ofid/ofz397

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title = "Pathogen-Negative Sepsis-An Opportunity for Antimicrobial Stewardship",

abstract = "Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4-9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.",

keywords = "pathogen-negative, sepsis, stewardship",

author = "Lockhart, \{Gabriel C.\} and Jacob Hanin and Micek, \{Scott T.\} and Kollef, \{Marin H.\}",

note = "Funding Information: Financial support. Dr. Kollef's efforts were supported by the Barnes-Jewish Hospital Foundation. There are no other funding sources to report. Publisher Copyright: {\textcopyright} 2019 The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.",

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AU - Hanin, Jacob

AU - Micek, Scott T.

AU - Kollef, Marin H.

N1 - Funding Information: Financial support. Dr. Kollef's efforts were supported by the Barnes-Jewish Hospital Foundation. There are no other funding sources to report. Publisher Copyright: © 2019 The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

PY - 2019/10/1

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N2 - Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4-9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.

AB - Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4-9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.

KW - pathogen-negative

KW - sepsis

KW - stewardship

UR - https://www.scopus.com/pages/publications/85079684541

U2 - 10.1093/ofid/ofz397

DO - 10.1093/ofid/ofz397

M3 - Article

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AN - SCOPUS:85079684541

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JO - Open Forum Infectious Diseases

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IS - 10

M1 - ofz397

ER -

Pathogen-Negative Sepsis-An Opportunity for Antimicrobial Stewardship

Abstract

Keywords

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