Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation

Keyphrases

• Subsequent Generations 100%
• Δ9-tetrahydrocannabinol (Δ9-THC) 100%
• Striatal Synaptic Plasticity 100%
• Heroin Seeking 100%
• Germ Cells 50%
• Striatum 33%
• MRNA Expression 16%
• Protein Level 16%
• F1 Progeny 16%
• MRNA Level 16%
• N-methyl-D-aspartate Receptor (NMDAR) 16%
• Receptor Binding 16%
• Receptor Gene 16%
• Reward Sensitivity 16%
• Circuitry 16%
• Cannabis 16%
• Striatal 16%
• Stereotypic Behavior 16%
• Molecular Characteristics 16%
• Goal-directed Behavior 16%
• Causal Relationship 16%
• Dopamine Receptor 16%
• Behavior Modification 16%
• Adult Offspring 16%
• Excitatory Synapse 16%
• Cannabinoid Receptor 1 (CB1R) 16%
• Heroin 16%
• Neuronal Circuitry 16%
• Self-administer 16%
• Parental History 16%
• Dorsal Striatum 16%
• Neuronal Alterations 16%
• Glutamatergic Receptors 16%
• Compulsive Behavior 16%
• Cannabis Exposure 16%
• Risk for Psychiatric Disorder 16%
• Experimental Animal Studies 16%
• Adolescent Exposure 16%
• Offspring Phenotype 16%
• Heroin Withdrawal 16%
• Work Effort 16%

Neuroscience

• Synaptic Plasticity 100%
• Heroin 100%
• Tetrahydrocannabinol 100%
• Germ Cell 50%
• Striatum 33%
• Cannabis 33%
• Messenger RNA 33%
• Synapse 16%
• Behavior (Neuroscience) 16%
• Receptor Gene 16%
• Receptor Binding 16%
• NMDA Receptor 16%
• Mental Disorder 16%
• Dorsal Striatum 16%
• Compulsive Behavior 16%
• Stereotypy 16%
• Cannabinoid 16%