Parathyroid hormone activation of stretch-activated cation channels in osteosarcoma cells (UMR-106.01)

Randall L. Duncan, Keith A. Hruska, Stanley Misler

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Cell-attached patches of membrane of osteoblast-like cells UMR-106.01 respond to bath application of parathyroid hormone (PTH) with an increase in the average activity, as well as the single channel conductance, of a stretch-activated non-selective cation channel. Correlations with whole cell membrane potential and conductance changes are considered.

Original languageEnglish
Pages (from-to)219-223
Number of pages5
JournalFEBS Letters
Volume307
Issue number2
DOIs
StatePublished - Jul 28 1992
Externally publishedYes

Keywords

  • Cyclic AMP
  • Osteoblastic cell line
  • Parathyroid hormone
  • Stretch-activatcd channel

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