Parafollicular cells in the normal human thyroid

Steven L. Teitelbaum, Kenneth E. Moore, William Shieber

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

NONIDEZ1 has described argyrophyllic, granulated cells distinct from follicular cells in the dog thyroid. It is now known that the mammalian thyroid is a source of calcitonin2, and the parafollicular cells seem to produce thyrocalcitonin3,4. Although calcitonin activity has been demonstrated in human thyroid tissue5, the parafollicular cells of the human thyroid have never before been demonstrated. Their presence has been assumed, however, because medullary carcinoma of the thyroid consists of cells resembling the parafollicular cells of other mammalian species, and contains calcitonin activity6.

Original languageEnglish
Pages (from-to)334-335
Number of pages2
JournalNature
Volume230
Issue number5292
DOIs
StatePublished - Dec 1 1971

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