Pain Wars: A New Hope

Kyle E. Parker; Michael R. Bruchas

doi:10.1016/j.neuron.2018.11.045

Pain Wars: A New Hope

Kyle E. Parker, Michael R. Bruchas

Division of Pain Research

Research output: Contribution to journal › Short survey › peer-review

Abstract

Nociceptin opioid peptide receptor agonists interact with mu-opioid receptor agonists for pain relief. A new study by Ding et al. (2018) examines a bifunctional nociceptin- and mu-opioid receptor agonist, AT-121, that provides analgesia without physiological side effects or abuse liability, offering a promising new hope toward better analgesics.

Original language	English
Pages (from-to)	1280-1282
Number of pages	3
Journal	Neuron
Volume	100
Issue number	6
DOIs	https://doi.org/10.1016/j.neuron.2018.11.045
State	Published - Dec 19 2018

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title = "Pain Wars: A New Hope",

abstract = "Nociceptin opioid peptide receptor agonists interact with mu-opioid receptor agonists for pain relief. A new study by Ding et al. (2018) examines a bifunctional nociceptin- and mu-opioid receptor agonist, AT-121, that provides analgesia without physiological side effects or abuse liability, offering a promising new hope toward better analgesics.",

author = "Parker, {Kyle E.} and Bruchas, {Michael R.}",

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T2 - A New Hope

AU - Parker, Kyle E.

AU - Bruchas, Michael R.

PY - 2018/12/19

Y1 - 2018/12/19

N2 - Nociceptin opioid peptide receptor agonists interact with mu-opioid receptor agonists for pain relief. A new study by Ding et al. (2018) examines a bifunctional nociceptin- and mu-opioid receptor agonist, AT-121, that provides analgesia without physiological side effects or abuse liability, offering a promising new hope toward better analgesics.

AB - Nociceptin opioid peptide receptor agonists interact with mu-opioid receptor agonists for pain relief. A new study by Ding et al. (2018) examines a bifunctional nociceptin- and mu-opioid receptor agonist, AT-121, that provides analgesia without physiological side effects or abuse liability, offering a promising new hope toward better analgesics.

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U2 - 10.1016/j.neuron.2018.11.045

DO - 10.1016/j.neuron.2018.11.045

M3 - Short survey

C2 - 30571940

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SN - 0896-6273

VL - 100

SP - 1280

EP - 1282

JO - Neuron

JF - Neuron

IS - 6

ER -

Pain Wars: A New Hope

Abstract

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