Pain Wars: A New Hope

Kyle E. Parker, Michael R. Bruchas

Research output: Contribution to journalShort surveypeer-review


Nociceptin opioid peptide receptor agonists interact with mu-opioid receptor agonists for pain relief. A new study by Ding et al. (2018) examines a bifunctional nociceptin- and mu-opioid receptor agonist, AT-121, that provides analgesia without physiological side effects or abuse liability, offering a promising new hope toward better analgesics.

Original languageEnglish
Pages (from-to)1280-1282
Number of pages3
Issue number6
StatePublished - Dec 19 2018

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