Oxytocin-a multifunctional analgesic for chronic deep tissue pain

Burel R. Goodin; Timothy J. Ness; Meredith T. Robbins

doi:10.2174/1381612820666141027111843

Oxytocin-a multifunctional analgesic for chronic deep tissue pain

Burel R. Goodin
, Timothy J. Ness
, Meredith T. Robbins

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

The treatment of chronic pain arising from deep tissues is currently inadequate and there is need for new pharmacological agents to provide analgesia. The endogenous paracrine hormone/neurotransmitter oxytocin is intimately involved in the modulation of multiple physiological and psychological functions. Recent experiments have given clear evidence for a role of oxytocin in the modulation of nociception. The present article reviews the existent human and basic science data related to the direct and indirect effects of oxytocin on pain.

Original language	English
Pages (from-to)	906-913
Number of pages	8
Journal	Current Pharmaceutical Design
Volume	21
Issue number	7
DOIs	https://doi.org/10.2174/1381612820666141027111843
State	Published - Jan 1 2015

Keywords

Analgesics
Anxiolytics
Musculoskeletal pain
Nociception
Oxytocin
Visceral pain

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10.2174/1381612820666141027111843

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abstract = "The treatment of chronic pain arising from deep tissues is currently inadequate and there is need for new pharmacological agents to provide analgesia. The endogenous paracrine hormone/neurotransmitter oxytocin is intimately involved in the modulation of multiple physiological and psychological functions. Recent experiments have given clear evidence for a role of oxytocin in the modulation of nociception. The present article reviews the existent human and basic science data related to the direct and indirect effects of oxytocin on pain.",

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KW - Analgesics

KW - Anxiolytics

KW - Musculoskeletal pain

KW - Nociception

KW - Oxytocin

KW - Visceral pain

UR - https://www.scopus.com/pages/publications/84925882340

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Oxytocin-a multifunctional analgesic for chronic deep tissue pain

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Keywords

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