Oxidation of sulfides with N-bromosuccinimide in the presence of hydrated silica gel

Mohammed Hashmat Ali; Melanie Hartman; Kimberly Lamp; Chad Schmitz; Tim Wencewicz

doi:10.1080/00397910600618988

Oxidation of sulfides with N-bromosuccinimide in the presence of hydrated silica gel

Mohammed Hashmat Ali
, Melanie Hartman
, Kimberly Lamp
, Chad Schmitz
, Tim Wencewicz

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

An efficient and highly selective procedure for oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) in the presence of hydrated silica gel has been developed. Hydrated silica gel supplies the water necessary for decomposition of the intermediate bromosulfonium salt to the product, allowing the reaction to employ a nonaqueous media. Also, this procedure has increased the scope of the reaction by oxidizing a wider variety of sulfides, which was not possible until now.

Original language	English
Pages (from-to)	1769-1777
Number of pages	9
Journal	Synthetic Communications
Volume	36
Issue number	12
DOIs	https://doi.org/10.1080/00397910600618988
State	Published - 2006

Keywords

N-Bromosuccinimide
NBS
Oxidation
Silica gel
Sulfides
Sulfoxides

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10.1080/00397910600618988

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title = "Oxidation of sulfides with N-bromosuccinimide in the presence of hydrated silica gel",

abstract = "An efficient and highly selective procedure for oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) in the presence of hydrated silica gel has been developed. Hydrated silica gel supplies the water necessary for decomposition of the intermediate bromosulfonium salt to the product, allowing the reaction to employ a nonaqueous media. Also, this procedure has increased the scope of the reaction by oxidizing a wider variety of sulfides, which was not possible until now.",

keywords = "N-Bromosuccinimide, NBS, Oxidation, Silica gel, Sulfides, Sulfoxides",

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T1 - Oxidation of sulfides with N-bromosuccinimide in the presence of hydrated silica gel

AU - Ali, Mohammed Hashmat

AU - Hartman, Melanie

AU - Lamp, Kimberly

AU - Schmitz, Chad

AU - Wencewicz, Tim

PY - 2006

Y1 - 2006

N2 - An efficient and highly selective procedure for oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) in the presence of hydrated silica gel has been developed. Hydrated silica gel supplies the water necessary for decomposition of the intermediate bromosulfonium salt to the product, allowing the reaction to employ a nonaqueous media. Also, this procedure has increased the scope of the reaction by oxidizing a wider variety of sulfides, which was not possible until now.

AB - An efficient and highly selective procedure for oxidation of sulfides to sulfoxides with N-bromosuccinimide (NBS) in the presence of hydrated silica gel has been developed. Hydrated silica gel supplies the water necessary for decomposition of the intermediate bromosulfonium salt to the product, allowing the reaction to employ a nonaqueous media. Also, this procedure has increased the scope of the reaction by oxidizing a wider variety of sulfides, which was not possible until now.

KW - N-Bromosuccinimide

KW - NBS

KW - Oxidation

KW - Silica gel

KW - Sulfides

KW - Sulfoxides

UR - https://www.scopus.com/pages/publications/33646807794

U2 - 10.1080/00397910600618988

DO - 10.1080/00397910600618988

M3 - Article

AN - SCOPUS:33646807794

SN - 0039-7911

VL - 36

SP - 1769

EP - 1777

JO - Synthetic Communications

JF - Synthetic Communications

IS - 12

ER -

Oxidation of sulfides with N-bromosuccinimide in the presence of hydrated silica gel

Abstract

Keywords

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