Oxidation Driven Reversal of PIP₂-dependent Gating in GIRK2 Channels

Keyphrases

• Phosphatidylinositol 4,5-bisphosphate (PIP2) 100%
• GIRK2 Channels 100%
• Na + 60%
• Basal Activity 60%
• Inward Rectifier Potassium Channel 40%
• Pathophysiologic 20%
• Mutagenesis 20%
• Neurotransmitters 20%
• Physiological Function 20%
• Myocytes 20%
• G Protein 20%
• Kir2.3 20%
• Phosphoinositol 20%
• Electrical Response 20%
• GIRK2 20%
• Cysteine Residues 20%
• 5-bisphosphate 20%
• Reducing Environment 20%
• Oxidizing Conditions 20%
• Kir3 Channels 20%
• Anomalous Behavior 20%

Biochemistry, Genetics and Molecular Biology

• Inward-Rectifier Potassium Ion Channel 100%
• Agonist 50%
• Mutagenesis 50%
• Potassium Channel 50%
• Neurotransmitter 50%
• Cysteine 50%
• G Protein 50%
• Inositol Phosphate 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Sodium Ion 100%
• Potassium Ion 33%
• Cysteine 33%
• Potassium Channel 33%
• Neurotransmitter 33%
• Guanine Nucleotide Binding Protein 33%
• Mutagenesis 33%
• Inositol Phosphate 33%