Overview of the Lens

J. Fielding Hejtmancik, Alan Shiels

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

48 Scopus citations


In order to accomplish its function of transmitting and focusing light, the crystalline lens of the vertebrate eye has evolved a unique cellular structure and protein complement. These distinct adaptations have provided a rich source of scientific discovery ranging from biochemistry and genetics to optics and physics. In addition, because of these adaptations, lens cells persist for the lifetime of an organism, providing an excellent model of the aging process. The chapters dealing with the lens will demonstrate how the different aspects of lens biology and biochemistry combine in this singular refractive organ to accomplish its critical role in the visual system.

Original languageEnglish
Title of host publicationMolecular Biology of Eye Disease, 2015
EditorsJohn M. Nickerson, J. Fielding Hejtmancik
PublisherElsevier B.V.
Number of pages9
ISBN (Print)9780128010594
StatePublished - 2015

Publication series

NameProgress in Molecular Biology and Translational Science
ISSN (Print)1877-1173
ISSN (Electronic)1878-0814


  • Biochemistry
  • Cell biology
  • Development
  • Genetics
  • Lens


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