Ovarian tissue characterization using bulk optical properties

  • B. Tavakoli
  • , Y. Xu
  • , Q. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Ovarian cancer, the deadliest of all gynecologic cancers, is not often found in its early stages due to few symptoms and no reliable screening test. Optical imaging has a great potential to improve the ovarian cancer detection and diagnosis. In this study we have characterized the bulk optical properties of 26 ex-vivo human ovaries using a Diffuse Optical Tomography system. The quantitative values indicated that, in the postmenopausal group, malignant ovaries showed significantly lower scattering coefficient than normal ones. The scattering parameter is largely related to the collagen content that has shown a strong correlation with the cancer development.

Original languageEnglish
Title of host publicationOptical Tomography and Spectroscopy of Tissue X
DOIs
StatePublished - 2013
EventOptical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States
Duration: Feb 3 2013Feb 6 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8578
ISSN (Print)1605-7422

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue X
Country/TerritoryUnited States
CitySan Francisco, CA
Period02/3/1302/6/13

Keywords

  • Diffuse optical imaging
  • optical absorption
  • optical scattering
  • ovarian cancer

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