Outcomes of Stage I/II vulvar cancer patients after negative superficial inguinal lymphadenectomy

Tyler O. Kirby, Rodney P. Rocconi, T. Michael Numnum, James E. Kendrick, Jason Wright, Wiley Fowler, David G. Mutch, Snehal M. Bhoola, Warner K. Huh, J. Michael Straughn

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

Objectives. To investigate the patterns of recurrence associated with superficial inguinal lymphadenectomy (SupIL) and vulvectomy for patients with Stage I/II vulvar cancer. Methods. A retrospective chart review identified patients from 1990-2001 with Stage I/II vulvar cancer that underwent SupIL and vulvectomy. Survival was analyzed using the Kaplan-Meier method with Fisher Exact and Chi-square tests for comparisons between groups. Results. 65 patients with Stage I/II vulvar cancer with a pathologically negative SupIL were identified (30 Stage I, 35 Stage II). Three patients recurred in the inguinal region, (4.6%) and 11 patients (16.9%) recurred on the vulva. Two of the 11 patients died of disease, six patients are alive without evidence of disease after additional therapy. Five-year disease-free survival and overall survival were 66% and 97%, respectively. Risk of recurrence was not associated with smoking status, stage, or margin status. Conclusions. SupIL and vulvectomy for Stage I/II vulvar cancer have a low recurrence rate in the inguinal region when nodes are negative. The local recurrence rate (17%) is acceptable, and overall survival is good using this conservative approach.

Original languageEnglish
Pages (from-to)309-312
Number of pages4
JournalGynecologic oncology
Volume98
Issue number2
DOIs
StatePublished - Aug 2005

Keywords

  • Lymphedema
  • Superficial inguinal lymphadenectomy
  • Vulvar cancer
  • Vulvectomy

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