OUTCOMES ASSOCIATED WITH PERCUTANEOUS CORONARY INTERVENTION PRIOR TO TRANSCATHETER AORTIC VALVE IMPLANTATION

Manoj Thangam, Prashanth Thakker, Mustafa Husaini, John Posenau, Marc Sintek, Puja Kachroo, John Lasala, Spencer Melby, Nishath Quader, Hersh Maniar, Jasvindar Singh, Howard Kurz, Richard Bach, Amit Amin, Alan Zajarias

Research output: Contribution to journalConference articlepeer-review

Abstract

Background: Coronary artery disease (CAD) is encountered in 40-75% of those undergoing transcatheter aortic valve replacement (TAVR). However, the safety of percutaneous coronary intervention (PCI) prior to TAVR is unclear. Methods: A retrospective analysis of patients with PCI < 6 months prior to TAVR from 1/1/2013- 1/1/2018 was done. Data were abstracted including demographics, procedural outcomes, and survival. Patients were stratified based on history of CABG and univariate analysis of demographic data was performed. PCI complications were defined by bleeding, vascular damage, and stroke. TAVR complications also included permanent pacemaker implantation. VARC 2 complications, survival at 6 months, and survival at 1 year were evaluated using the Chi-Square test with stratification by Syntax score (0-22, 23-32, >32) and Society of Thoracic Surgeon risk score (low <3, moderate=3-8, high>8). Results: A total of 103 patients underwent PCI < 6 months prior to TAVR (80 non-CABG, 23 CABG). Baseline characteristics were similar in regard to diabetes, hypertension, prior myocardial infarction, lung disease, peripheral artery disease, stroke and left ventricular ejection fraction. Results are shown in Table 1. The safety and efficacy of PCI was not influenced by timing of PCI (< 6 months vs. < 1 month), STS score, or Syntax score. Conclusion In selected patients with aortic stenosis, treatment of concomitant CAD within 6 months is feasible and safe despite lesion complexity or patient risk class.

Original languageEnglish
Pages (from-to)1315
Number of pages1
JournalJournal of the American College of Cardiology
Volume73
Issue number9
DOIs
StatePublished - Mar 12 2019
EventThe American College of Cardiology 68th Annual Scientific Sessions - New Orleans, United States
Duration: Mar 16 2019Mar 18 2019

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