TY - JOUR
T1 - OUTCOMES ASSOCIATED WITH PERCUTANEOUS CORONARY INTERVENTION PRIOR TO TRANSCATHETER AORTIC VALVE IMPLANTATION
AU - Thangam, Manoj
AU - Thakker, Prashanth
AU - Husaini, Mustafa
AU - Posenau, John
AU - Sintek, Marc
AU - Kachroo, Puja
AU - Lasala, John
AU - Melby, Spencer
AU - Quader, Nishath
AU - Maniar, Hersh
AU - Singh, Jasvindar
AU - Kurz, Howard
AU - Bach, Richard
AU - Amin, Amit
AU - Zajarias, Alan
N1 - Publisher Copyright:
© 2019 American College of Cardiology Foundation
PY - 2019/3/12
Y1 - 2019/3/12
N2 - Background: Coronary artery disease (CAD) is encountered in 40-75% of those undergoing transcatheter aortic valve replacement (TAVR). However, the safety of percutaneous coronary intervention (PCI) prior to TAVR is unclear. Methods: A retrospective analysis of patients with PCI < 6 months prior to TAVR from 1/1/2013- 1/1/2018 was done. Data were abstracted including demographics, procedural outcomes, and survival. Patients were stratified based on history of CABG and univariate analysis of demographic data was performed. PCI complications were defined by bleeding, vascular damage, and stroke. TAVR complications also included permanent pacemaker implantation. VARC 2 complications, survival at 6 months, and survival at 1 year were evaluated using the Chi-Square test with stratification by Syntax score (0-22, 23-32, >32) and Society of Thoracic Surgeon risk score (low <3, moderate=3-8, high>8). Results: A total of 103 patients underwent PCI < 6 months prior to TAVR (80 non-CABG, 23 CABG). Baseline characteristics were similar in regard to diabetes, hypertension, prior myocardial infarction, lung disease, peripheral artery disease, stroke and left ventricular ejection fraction. Results are shown in Table 1. The safety and efficacy of PCI was not influenced by timing of PCI (< 6 months vs. < 1 month), STS score, or Syntax score. Conclusion In selected patients with aortic stenosis, treatment of concomitant CAD within 6 months is feasible and safe despite lesion complexity or patient risk class.
AB - Background: Coronary artery disease (CAD) is encountered in 40-75% of those undergoing transcatheter aortic valve replacement (TAVR). However, the safety of percutaneous coronary intervention (PCI) prior to TAVR is unclear. Methods: A retrospective analysis of patients with PCI < 6 months prior to TAVR from 1/1/2013- 1/1/2018 was done. Data were abstracted including demographics, procedural outcomes, and survival. Patients were stratified based on history of CABG and univariate analysis of demographic data was performed. PCI complications were defined by bleeding, vascular damage, and stroke. TAVR complications also included permanent pacemaker implantation. VARC 2 complications, survival at 6 months, and survival at 1 year were evaluated using the Chi-Square test with stratification by Syntax score (0-22, 23-32, >32) and Society of Thoracic Surgeon risk score (low <3, moderate=3-8, high>8). Results: A total of 103 patients underwent PCI < 6 months prior to TAVR (80 non-CABG, 23 CABG). Baseline characteristics were similar in regard to diabetes, hypertension, prior myocardial infarction, lung disease, peripheral artery disease, stroke and left ventricular ejection fraction. Results are shown in Table 1. The safety and efficacy of PCI was not influenced by timing of PCI (< 6 months vs. < 1 month), STS score, or Syntax score. Conclusion In selected patients with aortic stenosis, treatment of concomitant CAD within 6 months is feasible and safe despite lesion complexity or patient risk class.
UR - http://www.scopus.com/inward/record.url?scp=85201019296&partnerID=8YFLogxK
U2 - 10.1016/S0735-1097(19)31922-9
DO - 10.1016/S0735-1097(19)31922-9
M3 - Conference article
AN - SCOPUS:85201019296
SN - 0735-1097
VL - 73
SP - 1315
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 9
T2 - The American College of Cardiology 68th Annual Scientific Sessions
Y2 - 16 March 2019 through 18 March 2019
ER -