Outcomes after cataract surgery in eyes with pseudoexfoliation: Results from the Veterans Affairs Ophthalmic Surgery Outcomes Data Project

Angela Turalba, Tulay Cakiner-Egilmez, Abhishek R. Payal, Luis A. Gonzalez-Gonzalez, Amy S. Chomsky, David E. Vollman, Elizabeth F. Baze, Mary G. Lawrence, Mary K. Daly

Research output: Contribution to journalArticle

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Abstract

Objective To compare clinical outcomes of cataract surgery in eyes with and without pseudoexfoliation (PXF). Design Retrospective deidentified data analysis. Participants A total of 123 PXF and 4776 non-PXF eyes of patients who underwent cataract surgery. Methods We compared data on visual acuity, Visual Function Questionnaire (VFQ)-based quality of life, and complications in PXF and non-PXF eyes from the Veterans Affairs (VA) Ophthalmic Surgery Outcomes Data Project across 5 VA medical centres. Results Pupillary expansion devices were used in 31 (25.2%) PXF cases and 398 (8.4%) non-PXF cases (p < 0.0001). Capsular tension rings were used in 6 (4.9%) PXF cases and 55 (1.2%) non-PXF cases (p < 0.004). The following complications occurred more frequently in PXF cases: zonular dehiscence without vitrectomy (4 [3.3%] PXF cases vs 40 [0.8%] non-PXF cases p = 0.02), persistent inflammation (28 [24.1%] vs 668 [14.5%]; p = 0.007), and persistent intraocular pressure elevation (5 [4.3%] vs 68 [1.5%]; p = 0.03). Best corrected visual acuity (BCVA) improved in both groups after 1 month, but 87 (83.7%) PXF cases achieved postoperative BCVA better than or equal to 20/40 compared to 3991 (93.8%) non-PXF cases (p = 0.0003). There was no significant difference in the postoperative composite VFQ scores between PXF (82.1 ± 16.9) and non-PXF cases (84.2 ± 16.8, p = 0.09). Conclusions Several complications occurred more frequently in the PXF group compared to the non-PXF group, and fewer PXF cases achieved BCVA better than or equal to 20/40. Despite this, both groups experienced similar improvement in vision-related quality of life after cataract surgery.

Original languageEnglish
Pages (from-to)61-68
Number of pages8
JournalCanadian Journal of Ophthalmology
Volume52
Issue number1
DOIs
StatePublished - Feb 1 2017

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    Turalba, A., Cakiner-Egilmez, T., Payal, A. R., Gonzalez-Gonzalez, L. A., Chomsky, A. S., Vollman, D. E., Baze, E. F., Lawrence, M. G., & Daly, M. K. (2017). Outcomes after cataract surgery in eyes with pseudoexfoliation: Results from the Veterans Affairs Ophthalmic Surgery Outcomes Data Project. Canadian Journal of Ophthalmology, 52(1), 61-68. https://doi.org/10.1016/j.jcjo.2016.07.019