The human gut is populated by a microbiota composed of tens of trillions of organisms and millions of genes that together form a metabolic "organ." Intra-and interpersonal differences in the structure and functions of this organ suggest thatit could contribute to our normal metabolic variations and also to metabolic disorders. This Commentary discusses experimental approaches for connecting microbial and host metabolism in the context of health and disease.

Original languageEnglish
Pages (from-to)111-116
Number of pages6
JournalCell metabolism
Issue number2
StatePublished - Aug 4 2010


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