Osteolytic paget's bone disease in a young man. Rapid healing with human calcitonin therapy

Michael P. Whyte, Ethan H. Daniels, William A. Murphy

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Paget's bone disease is rare in young adults. Severe osteolytic Paget's bone disease In a 28-year-old man was found to respond, clinically, biochemically, and radiographically, within one month to daily subcutaneous injections of 0.5 mg of synthetic human calcitonin. After two years of therapy, he remains asymptomatic and has no biochemical evidence of Paget's bone disease while receiving Injections three times a week. Despite aggressive disease, young patients may rapidly demonstrate the same beneficial response to synthetic human calcitonin therapy as has been observed in middle-aged or elderly patients with Paget's bone disease.

Original languageEnglish
Pages (from-to)326-332
Number of pages7
JournalThe American journal of medicine
Volume78
Issue number2
DOIs
StatePublished - Feb 1985

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