Osteoblastomatosis of bone. A benign, multifocal osteoblastic lesion, distinct from osteoid osteoma and osteoblastoma, radiologically simulating a vascular tumor

Michael Kyriakos, Georges Y. El-Khoury, Douglas J. McDonald, Joseph A. Buckwalter, Murali Sundaram, Barry DeYoung, Michael P. O'Brien

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Two adult patients are described with multifocal osteolytic lesions radiologically simulating a vascular tumor. One patient had multiple bones involved. Histologically, the individual lesions had the features of the nidus of osteoid osteoma/osteoblastoma. A review of the English language medical literature yielded only one other reported case with similar features. The process is designated as osteoblastomatosis to indicate its bone-forming character, prominent osteoblast proliferation, and multiplicity. The cases are distinguished from multifocal/ multicentric osteoid osteoma and osteoblastoma, and from benign and malignant vascular tumors.

Original languageEnglish
Pages (from-to)237-247
Number of pages11
JournalSkeletal Radiology
Volume36
Issue number3
DOIs
StatePublished - Mar 1 2007

Keywords

  • Angiomatosis
  • Hemangioendothelioma
  • Osteoblastoma
  • Osteoblastoma-likelesion
  • Osteoid osteoma

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