TY - JOUR
T1 - Orthobiologics in orthopedic applications
T2 - a report from the TMI Havemeyer meeting on orthobiologics
AU - Lattermann, Christian
AU - Leite, Chilan B.G.
AU - Frisbie, David D.
AU - Schlegel, Theodore S.
AU - Bramlage, Larry R.
AU - Koch, Thomas
AU - Centeno, Christopher
AU - Goodrich, Laurie R.
AU - Johnstone, Brian
AU - Trumper, Rocci
AU - Watts, Ashlee
AU - Little, Christopher
AU - Barry, Frank
AU - Guilak, Farsh
AU - McIlwraith, C. Wayne
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/9
Y1 - 2022/9
N2 - Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthopedic field by showing promising results. In order to review the current status of orthobiologics and to discuss the potential risks, benefits, and challenges of their implementation, a recent expert conference hosted by the C. Wayne McIlwraith Translational Medicine Institute (TMI), and funded by the Dorothy Havemeyer Foundation was held at Colorado State University, in conjunction with the official Opening of the TMI. This review summarizes the conference findings highlighting the scientific challenges, safety concerns, and translation of orthobiologics to clinical practice.
AB - Readily available and effective therapeutic approaches are increasingly required to overcome the growing demand for optimized management of musculoskeletal degenerative conditions. The use of biologic therapies has been gaining ground in the orthopedic field by showing promising results. In order to review the current status of orthobiologics and to discuss the potential risks, benefits, and challenges of their implementation, a recent expert conference hosted by the C. Wayne McIlwraith Translational Medicine Institute (TMI), and funded by the Dorothy Havemeyer Foundation was held at Colorado State University, in conjunction with the official Opening of the TMI. This review summarizes the conference findings highlighting the scientific challenges, safety concerns, and translation of orthobiologics to clinical practice.
KW - Orthobiologics
KW - Platelet-rich plasma
KW - Regenerative medicine
KW - Stem cell therapy
UR - http://www.scopus.com/inward/record.url?scp=85143488699&partnerID=8YFLogxK
U2 - 10.1016/j.jcjp.2022.100055
DO - 10.1016/j.jcjp.2022.100055
M3 - Article
AN - SCOPUS:85143488699
SN - 2667-2545
VL - 2
JO - Journal of Cartilage and Joint Preservation
JF - Journal of Cartilage and Joint Preservation
IS - 3
M1 - 100055
ER -