TY - JOUR
T1 - Origin, maturation and antigen presenting function of dendritic cells
AU - Cella, Marina
AU - Sallusto, Federica
AU - Lanzavecchia, Antonio
N1 - Funding Information:
We thank Christiane Ruedl and Marco Colonna for critical reading and comments. The Basel Institute for Immunology was founded and is supported by F Hoffmann-La Roche, Basel, Switzerland.
PY - 1997/2
Y1 - 1997/2
N2 - Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.
AB - Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.
UR - http://www.scopus.com/inward/record.url?scp=0031045622&partnerID=8YFLogxK
U2 - 10.1016/S0952-7915(97)80153-7
DO - 10.1016/S0952-7915(97)80153-7
M3 - Article
C2 - 9039784
AN - SCOPUS:0031045622
SN - 0952-7915
VL - 9
SP - 10
EP - 16
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 1
ER -