Organocatalytic kinetic resolution of N-boc-isoxazolidine-5-ones

Matthew R. Straub; Vladimir B. Birman

doi:10.1021/acs.orglett.0c04196

Organocatalytic kinetic resolution of N-boc-isoxazolidine-5-ones

Matthew R. Straub
, Vladimir B. Birman

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, resulting in their effective kinetic resolution.

Original language	English
Pages (from-to)	984-988
Number of pages	5
Journal	Organic Letters
Volume	23
Issue number	3
DOIs	https://doi.org/10.1021/acs.orglett.0c04196
State	Published - Feb 5 2021

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title = "Organocatalytic kinetic resolution of N-boc-isoxazolidine-5-ones",

abstract = "Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, resulting in their effective kinetic resolution.",

author = "Straub, \{Matthew R.\} and Birman, \{Vladimir B.\}",

note = "Publisher Copyright: {\textcopyright} 2021 American Chemical Society",

year = "2021",

month = feb,

day = "5",

doi = "10.1021/acs.orglett.0c04196",

language = "English",

volume = "23",

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journal = "Organic Letters",

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T1 - Organocatalytic kinetic resolution of N-boc-isoxazolidine-5-ones

AU - Straub, Matthew R.

AU - Birman, Vladimir B.

PY - 2021/2/5

Y1 - 2021/2/5

N2 - Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, resulting in their effective kinetic resolution.

AB - Easily accessible racemic N-Boc-isoxazolidine-5-ones undergo enantioselective alcoholysis promoted by double hydrogen bond donor amine organocatalysts, resulting in their effective kinetic resolution.

UR - https://www.scopus.com/pages/publications/85100237242

U2 - 10.1021/acs.orglett.0c04196

DO - 10.1021/acs.orglett.0c04196

M3 - Article

C2 - 33476151

AN - SCOPUS:85100237242

SN - 1523-7060

VL - 23

SP - 984

EP - 988

JO - Organic Letters

JF - Organic Letters

IS - 3

ER -

Organocatalytic kinetic resolution of N-boc-isoxazolidine-5-ones

Abstract

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