Organizing knowledge to enable personalization of medicine in cancer

Benjamin M. Good; Benjamin J. Ainscough; Josh F. McMichael; Andrew I. Su; Obi L. Griffith

doi:10.1186/s13059-014-0438-7

Organizing knowledge to enable personalization of medicine in cancer

Benjamin M. Good
, Benjamin J. Ainscough
, Josh F. McMichael
, Andrew I. Su
, Obi L. Griffith

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.

Original language	English
Article number	438
Journal	Genome biology
Volume	15
Issue number	8
DOIs	https://doi.org/10.1186/s13059-014-0438-7
State	Published - Aug 27 2014

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title = "Organizing knowledge to enable personalization of medicine in cancer",

abstract = "Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.",

author = "Good, \{Benjamin M.\} and Ainscough, \{Benjamin J.\} and McMichael, \{Josh F.\} and Su, \{Andrew I.\} and Griffith, \{Obi L.\}",

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T1 - Organizing knowledge to enable personalization of medicine in cancer

AU - Good, Benjamin M.

AU - Ainscough, Benjamin J.

AU - McMichael, Josh F.

AU - Su, Andrew I.

AU - Griffith, Obi L.

PY - 2014/8/27

Y1 - 2014/8/27

N2 - Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.

AB - Interpretation of the clinical significance of genomic alterations remains the most severe bottleneck preventing the realization of personalized medicine in cancer. We propose a knowledge commons to facilitate collaborative contributions and open discussion of clinical decision-making based on genomic events in cancer.

UR - https://www.scopus.com/pages/publications/84922210982

U2 - 10.1186/s13059-014-0438-7

DO - 10.1186/s13059-014-0438-7

M3 - Article

C2 - 25222080

AN - SCOPUS:84922210982

SN - 1474-7596

VL - 15

JO - Genome biology

JF - Genome biology

IS - 8

M1 - 438

ER -

Organizing knowledge to enable personalization of medicine in cancer

Abstract

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