Orbital metastasis in advanced gallbladder and biliary tract malignancy

Aashray Singareddy; George J. Harocopos; Steven M. Couch; Carol Goetz; Olivia Aranha

doi:10.1136/bcr-2025-265765

Orbital metastasis in advanced gallbladder and biliary tract malignancy

Aashray Singareddy
, George J. Harocopos
, Steven M. Couch
, Carol Goetz
, Olivia Aranha

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Orbital metastases are a rare site of spread for most malignancies. Here, we present an unusual case of an orbital mass as the first presenting sign of metastatic gallbladder and biliary tract cancer. MRI, positron emission tomography and tumour biopsy were used to establish the diagnosis. Treatment was started with chemoimmunotherapy, and radiation was deferred. Subsequent imaging showed tumour response to treatment.

Original language	English
Article number	e265765
Journal	BMJ Case Reports
Volume	18
Issue number	7
DOIs	https://doi.org/10.1136/bcr-2025-265765
State	Published - Jul 20 2025

Keywords

Chemotherapy
Pancreas and biliary tract

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10.1136/bcr-2025-265765

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title = "Orbital metastasis in advanced gallbladder and biliary tract malignancy",

abstract = "Orbital metastases are a rare site of spread for most malignancies. Here, we present an unusual case of an orbital mass as the first presenting sign of metastatic gallbladder and biliary tract cancer. MRI, positron emission tomography and tumour biopsy were used to establish the diagnosis. Treatment was started with chemoimmunotherapy, and radiation was deferred. Subsequent imaging showed tumour response to treatment.",

keywords = "Chemotherapy, Pancreas and biliary tract",

author = "Aashray Singareddy and Harocopos, \{George J.\} and Couch, \{Steven M.\} and Carol Goetz and Olivia Aranha",

note = "Publisher Copyright: {\textcopyright} BMJ Publishing Group Limited 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.",

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AU - Singareddy, Aashray

AU - Harocopos, George J.

AU - Couch, Steven M.

AU - Goetz, Carol

AU - Aranha, Olivia

N1 - Publisher Copyright: © BMJ Publishing Group Limited 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.

PY - 2025/7/20

Y1 - 2025/7/20

N2 - Orbital metastases are a rare site of spread for most malignancies. Here, we present an unusual case of an orbital mass as the first presenting sign of metastatic gallbladder and biliary tract cancer. MRI, positron emission tomography and tumour biopsy were used to establish the diagnosis. Treatment was started with chemoimmunotherapy, and radiation was deferred. Subsequent imaging showed tumour response to treatment.

AB - Orbital metastases are a rare site of spread for most malignancies. Here, we present an unusual case of an orbital mass as the first presenting sign of metastatic gallbladder and biliary tract cancer. MRI, positron emission tomography and tumour biopsy were used to establish the diagnosis. Treatment was started with chemoimmunotherapy, and radiation was deferred. Subsequent imaging showed tumour response to treatment.

KW - Chemotherapy

KW - Pancreas and biliary tract

UR - https://www.scopus.com/pages/publications/105011325087

U2 - 10.1136/bcr-2025-265765

DO - 10.1136/bcr-2025-265765

M3 - Article

C2 - 40685225

AN - SCOPUS:105011325087

SN - 1757-790X

VL - 18

JO - BMJ Case Reports

JF - BMJ Case Reports

IS - 7

M1 - e265765

ER -

Orbital metastasis in advanced gallbladder and biliary tract malignancy

Abstract

Keywords

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