Optimal equations for describing the relationship between prostate volume, number of sources, and total activity in permanent prostate brachytherapy

Jesse N. Aronowitz, Jeff M. Michalski, Gregory S. Merrick, John E. Sylvester, Juanita M. Crook, Wayne M. Butler, Christie Mawson, David Pratt, Devi Naidoo, Kathryn Karolczuk

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Objectives: To determine whether there is an optimal type of mathematical equation for predicting seed and activity requirements for permanent prostate brachytherapy. Methods: Four institutions with extensive brachytherapy experience each submitted details of more than 40 implants. The data was used to generate power and linear equations to reflect the relationship between preimplant volume and the number of seeds implanted, and preimplant volume and the total implant activity. We compared the R and standard error of the generated equations to determine which type of equation better fit the data. Results: For the limited range of prostate volumes commonly implanted (20-60 mL), power and linear equations predict seed and activity requirements comparably well. Conclusions: Linear and power equations are equally suitable for generating institution-specific nomograms.

Original languageEnglish
Pages (from-to)164-167
Number of pages4
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume33
Issue number2
DOIs
StatePublished - Apr 1 2010

Keywords

  • Brachytherapy
  • Dosimetry
  • Prostatic neoplasms

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