@inproceedings{890121d511bf44408e6a3ef409826432,
title = "Online phenotype discovery in high-content RNAi screens using gap statistics",
abstract = "Discovering and identifying novel phenotypes from images inputting online is a major challenge in high-content RNA interference (RNAi) screens. Discovered phenotypes should be visually distinct from existing ones and make biological sense. An online phenotype discovery method featuring adaptive phenotype modeling and iterative cluster merging using gap statistics is proposed. The method works well on discovering new phenotypes adaptively when applied to both of synthetic data sets and RNAi high content screen (HCS) images with ground truth labels.",
keywords = "Gap statistics, High content screen, Phenotype discovery, RNA interference",
author = "Zheng Yin and Xiaobo Zhou and Chris Bakal and Fuhai Li and Youxian Sun and Norbert Perrimon and Wong, {Stephen T.C.}",
year = "2007",
doi = "10.1063/1.2816647",
language = "English",
isbn = "9780735404663",
series = "AIP Conference Proceedings",
pages = "86--95",
booktitle = "Computational Models For Life Sciences (CMLS '07) - 2007 International Symposium",
note = "2007 International Symposium on Computational Models for Life Sciences, CMLS '07 ; Conference date: 17-12-2007 Through 19-12-2007",
}