One-pot synthesis of pyrrole derivatives from (E)-1,4-diaryl-2-butene-1,4-diones

H. Surya Prakash Rao, S. Jothilingam

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

2,5-Di- and 1,2,5-trisubstituted pyrrole derivatives can be prepared conveniently from (E)-1,4-diaryl-2-butene-1,4-diones in a one-pot operation through domino-pathways via palladium-assisted transfer hydrogenation followed by a Paal-Knorr reaction using ammonium formate and its analogs.

Original languageEnglish
Pages (from-to)6595-6597
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number37
DOIs
StatePublished - Sep 10 2001

Keywords

  • Microwave
  • Paal-Knorr reaction
  • Substituted pyrroles
  • Transfer hydrogenation

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