Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy

Nathan H. Kung; Robert C. Bucelli; Collin M. McClelland; Gregory P. Van Stavern

doi:10.3109/01658107.2015.1059464

Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy

Nathan H. Kung, Robert C. Bucelli, Collin M. McClelland, Gregory P. Van Stavern

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6 Scopus citations

Abstract

Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.

Original language	English
Pages (from-to)	240-242
Number of pages	3
Journal	Neuro-Ophthalmology
Volume	39
Issue number	5
DOIs	https://doi.org/10.3109/01658107.2015.1059464
State	Published - Sep 3 2015

Keywords

Chronic inflammatory demyelinating polyneuropathy
diplopia
ocular motility
ocular neuromyotonia

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title = "Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy",

abstract = "Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.",

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AU - Bucelli, Robert C.

AU - McClelland, Collin M.

AU - Van Stavern, Gregory P.

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AB - Ocular neuromyotonia (ONM) is a neuro-ophthalmic disorder characterized by episodic diplopia caused by contraction of one or more ocular muscles due to spontaneous excitation of the respective ocular motor nerve. We report a patient whose ocular neuromyotonia arose in the setting of a subacute demyelinating polyneuropathy consistent with chronic inflammatory demyelinating polyneuropathy (CIDP) and subsequently resolved following the initiation of intravenous immunoglobulin (IVIg) for her neuropathy. Our patient provides additional evidence towards the role of demyelination and ephaptic neurotransmission in ocular neuromyotonia and also represents the first reported case of ocular neuromyotonia associated with a systemic neurological condition.

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Ocular Neuromyotonia Associated with Chronic Inflammatory Demyelinating Polyneuropathy

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