TY - JOUR
T1 - Obese children with steatohepatitis can develop cirrhosis in childhood
AU - Molleston, Jean P.
AU - White, Frances
AU - Teckman, Jeffrey
AU - Fitzgerald, Joseph F.
PY - 2002/9
Y1 - 2002/9
N2 - Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.
AB - Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.
UR - http://www.scopus.com/inward/record.url?scp=0036735880&partnerID=8YFLogxK
U2 - 10.1016/S0002-9270(02)04360-5
DO - 10.1016/S0002-9270(02)04360-5
M3 - Article
C2 - 12358273
AN - SCOPUS:0036735880
SN - 0002-9270
VL - 97
SP - 2460
EP - 2462
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 9
ER -