TY - JOUR
T1 - NutriConnect
T2 - Enhancing health and food security through sustainable solutions and partnerships: Design and protocol of a pragmatic comparative effectiveness trial
AU - Yoo, Sang Gune K.
AU - Tabak, Rachel G.
AU - Mazzucca-Ragan, Stephanie
AU - Primo, Allison
AU - Bohannon, Doneisha
AU - Hashimoto, Derek
AU - Goss, Charles W.
AU - Wu, Jason HY
AU - Eromosele, Eghonghon
AU - Hassanieh, Ihab
AU - Hively, Adam
AU - Martinez, Abygail
AU - Wang, Jinli
AU - Huffman, Mark D.
AU - Li, Jing
N1 - Publisher Copyright:
© 2025
PY - 2025/11
Y1 - 2025/11
N2 - Background: Food insecurity and poor dietary intake contribute to health disparities, particularly among socioeconomically disadvantaged populations. Produce prescription programs aim to improve access to fruits and vegetables (F&V) for those with diet-sensitive conditions, but comparative effectiveness data are limited. Objective: To compare the impact of two produce prescription strategies, NutriConnect Credit (grocery coupons) and NutriConnect Delivery (home-delivered F&V boxes), on dietary intake, food security, and health outcomes among socioeconomically disadvantaged populations who have been recently hospitalized with diet-sensitive conditions. Methods: In this three-arm pilot trial, recently hospitalized adults with food or financial insecurity and elevated cardiovascular risk were randomized (1:1:1) to Credit, Delivery, or enhanced usual care. The primary outcome is between group difference in change in F&V intake at 6 months. Secondary outcomes include food security and self-reported health-related quality of life. Implementation outcomes are assessed using the PRISM/RE-AIM framework. Conclusion: NutriConnect seeks to provide evidence on the effectiveness and feasibility of two produce prescription strategies to inform scalable “Food is Medicine” programs targeting nutrition-related health disparities.
AB - Background: Food insecurity and poor dietary intake contribute to health disparities, particularly among socioeconomically disadvantaged populations. Produce prescription programs aim to improve access to fruits and vegetables (F&V) for those with diet-sensitive conditions, but comparative effectiveness data are limited. Objective: To compare the impact of two produce prescription strategies, NutriConnect Credit (grocery coupons) and NutriConnect Delivery (home-delivered F&V boxes), on dietary intake, food security, and health outcomes among socioeconomically disadvantaged populations who have been recently hospitalized with diet-sensitive conditions. Methods: In this three-arm pilot trial, recently hospitalized adults with food or financial insecurity and elevated cardiovascular risk were randomized (1:1:1) to Credit, Delivery, or enhanced usual care. The primary outcome is between group difference in change in F&V intake at 6 months. Secondary outcomes include food security and self-reported health-related quality of life. Implementation outcomes are assessed using the PRISM/RE-AIM framework. Conclusion: NutriConnect seeks to provide evidence on the effectiveness and feasibility of two produce prescription strategies to inform scalable “Food is Medicine” programs targeting nutrition-related health disparities.
KW - Cardiovascular
KW - Disease prevention
KW - Food is Medicine
KW - Health equity
KW - Implementation science
KW - Nutrition incentives
KW - Randomized controlled trial
UR - https://www.scopus.com/pages/publications/105016818617
U2 - 10.1016/j.cct.2025.108083
DO - 10.1016/j.cct.2025.108083
M3 - Article
C2 - 40972889
AN - SCOPUS:105016818617
SN - 1551-7144
VL - 158
JO - Contemporary Clinical Trials
JF - Contemporary Clinical Trials
M1 - 108083
ER -