@inproceedings{e00c1a23c207432b9b524d34e6b6fd78,
title = "Numerical simulation of steady and pulsatile flow through models of vascular and aortic valve stenoses",
abstract = "A commercially available numerical flow solver {"}FLUENT{"} is employed in the simulation of blood flow through rigid models of vascular and aortic valve stenoses. For the vascular stenoses, in-vitro computations are performed for flow in axisymmetric and 3-D concentric flow phantoms for steady and pulsatile flow for 50%, 75% and 90% area stenoses at different flow rates, by considering the blood as a Newtonian fluid. The influence of stenosis on pressure distribution, velocity field and wall shear stress is examined for both steady and pulsatile flow (at 1 Hz). For axisymmetric stenoses, computations are compared with phase contrast MRI data; good agreement is obtained. The numerical results show the effect of flow rate and severity of stenosis on the pressure across the stenosis. Similar calculations (both steady and pulsatile at 3 Hz) are performed for a model of stenotic aortic valve by varying the flow rate and degree of stenosis to assess the range of validity of the Gorlin's equation. Based on the results, a modification to the Gorlin's equation is proposed that fits both the numerical and the limited experimental data for low and high flow rates as well as mild to severe stenosis.",
author = "Okpara, {Emmanuel C.} and Agarwal, {Ramesh K.}",
year = "2007",
doi = "10.2514/6.2007-4342",
language = "English",
isbn = "1563478978",
series = "Collection of Technical Papers - 37th AIAA Fluid Dynamics Conference",
publisher = "American Institute of Aeronautics and Astronautics Inc.",
pages = "1783--1799",
booktitle = "Collection of Technical Papers - 37th AIAA Fluid Dynamics Conference",
note = "37th AIAA Fluid Dynamics Conference ; Conference date: 25-06-2007 Through 28-06-2007",
}