Nucleic acid-triggered fluorescent probe activation by the staudinger reaction

Jianfeng Cai; Xiaoxu Li; Xuan Yue; John Stephen Taylor

doi:10.1021/ja0452626

Nucleic acid-triggered fluorescent probe activation by the staudinger reaction

Jianfeng Cai, Xiaoxu Li, Xuan Yue, John Stephen Taylor

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Highly sequence specific and sensitive detection systems for DNA or RNA in vivo would be of great use in biology and medicine for monitoring gene expression and diagnosing diseased cells. Herein we describe a new nucleic acid-triggered fluorescent probe system that is activated by a biocompatible and chemoselective Staudinger reaction.

Original language	English
Pages (from-to)	16324-16325
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	126
Issue number	50
DOIs	https://doi.org/10.1021/ja0452626
State	Published - Dec 22 2004

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title = "Nucleic acid-triggered fluorescent probe activation by the staudinger reaction",

abstract = "Highly sequence specific and sensitive detection systems for DNA or RNA in vivo would be of great use in biology and medicine for monitoring gene expression and diagnosing diseased cells. Herein we describe a new nucleic acid-triggered fluorescent probe system that is activated by a biocompatible and chemoselective Staudinger reaction.",

author = "Jianfeng Cai and Xiaoxu Li and Xuan Yue and Taylor, {John Stephen}",

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T1 - Nucleic acid-triggered fluorescent probe activation by the staudinger reaction

AU - Cai, Jianfeng

AU - Li, Xiaoxu

AU - Yue, Xuan

AU - Taylor, John Stephen

PY - 2004/12/22

Y1 - 2004/12/22

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AB - Highly sequence specific and sensitive detection systems for DNA or RNA in vivo would be of great use in biology and medicine for monitoring gene expression and diagnosing diseased cells. Herein we describe a new nucleic acid-triggered fluorescent probe system that is activated by a biocompatible and chemoselective Staudinger reaction.

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U2 - 10.1021/ja0452626

DO - 10.1021/ja0452626

M3 - Article

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JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 50

ER -

Nucleic acid-triggered fluorescent probe activation by the staudinger reaction

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