@article{bff54de8e2ab461a850893b0eea59b4b,
title = "Novelty, Salience, and Surprise Timing Are Signaled by Neurons in the Basal Forebrain",
abstract = "Zhang et al. show that cells in the primate basal forebrain (BF), an area that mediates activity of the neocortex, predict the timing of events that capture attention, such as surprising reinforcements and novel objects. After a salient event, other BF cells{\textquoteright} burst activations rapidly signal higher-order statistical information about motivational salience, novelty, and surprise.",
keywords = "attention, basal forebrain, motivation, neurophysiology, novelty, salience",
author = "Kaining Zhang and Chen, {Charles D.} and Monosov, {Ilya E.}",
note = "Funding Information: This work was supported by the National Institute of Mental Health under award number R01MH110594, the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) ElectRx program through the CMO grant/contract no. HR0011-16-2-0022, Edward Mallinckrodt, Jr. Foundation, and the McDonnell Center for Systems Neuroscience. We are grateful to Ms. Julia Pai, Dr. Noah Ledbetter, and Mr. J. Kael White for assisting in data acquisition, to Ms. Kim Kocher for fantastic animal care and training, and to Dr. Okihide Hikosaka and the National Eye Institute Intramural Research Program for supporting the recording experiments in monkeys H and P for a previous study [4]. We thank Ms. Julia Pai and Drs. Ethan Bromberg-Martin and Timothy Holy for helpful discussions and Dr. Hiroyuki Nakahara and Ms. Jamie Moffa for reading earlier versions of this manuscript. Funding Information: This work was supported by the National Institute of Mental Health under award number R01MH110594 , the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) ElectRx program through the CMO grant/contract no. HR0011-16-2-0022 , Edward Mallinckrodt, Jr. Foundation , and the McDonnell Center for Systems Neuroscience . We are grateful to Ms. Julia Pai, Dr. Noah Ledbetter, and Mr. J. Kael White for assisting in data acquisition, to Ms. Kim Kocher for fantastic animal care and training, and to Dr. Okihide Hikosaka and the National Eye Institute Intramural Research Program for supporting the recording experiments in monkeys H and P for a previous study [ 4 ]. We thank Ms. Julia Pai and Drs. Ethan Bromberg-Martin and Timothy Holy for helpful discussions and Dr. Hiroyuki Nakahara and Ms. Jamie Moffa for reading earlier versions of this manuscript. Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",
year = "2019",
month = jan,
day = "7",
doi = "10.1016/j.cub.2018.11.012",
language = "English",
volume = "29",
pages = "134--142.e3",
journal = "Current Biology",
issn = "0960-9822",
number = "1",
}