Novel treatments for cardiovascular disease prevention

Mark D. Huffman, Deepak Bhatnagar

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


The purpose of this review is to describe novel pharmacologic and nonpharmacologic preventive therapies, as well as new strategies to improve delivery of available therapies. Cardiovascular disease (CVD) is the leading cause of death worldwide, and prevention plays a critical role in curbing the global epidemic. Despite available treatment for tobacco addiction, platelet inhibition, blood pressure, and lipid lowering for reduction of atherosclerotic disease, significant gaps in treatment of total CVD remain. We review a range of new preventive treatment options, including drugs for tobacco cessation, platelet/thrombotic inhibition, lipid- and blood pressure-lowering; nonpharmacologic options such as left atrial appendage closure devices and caloric restriction; and strategies such as fixed-dose combination drugs, laboratory screening for drug tailoring, and community-based prevention programs. CVD preventive research continues to evolve and provide clinicians and patients with novel pharmacologic and nonpharmacologic therapies, including new preventive strategies.

Original languageEnglish
Pages (from-to)257-263
Number of pages7
JournalCardiovascular Therapeutics
Issue number5
StatePublished - Oct 2012


  • Cardiovascular disease
  • Novel
  • Prevention
  • Treatment


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