Novel synthesis of benzotriazolyl alkyl esters: an unprecedented CH2insertion

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Abstract

We have developed a novel method for the synthesis of benzotriazolyl alkyl esters (BAEs) fromN-acylbenzotriazoles and dichloromethane (DCM) under mild conditions. This reaction is one of few examples to show the use of DCM as a C-1 surrogate in carbon-heteroatom bond formation and to highlight the versatility of using DCM as a methylene building block.

Original languageEnglish
Pages (from-to)7564-7569
Number of pages6
JournalRSC Advances
Volume11
Issue number13
DOIs
StatePublished - Feb 17 2021

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