Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression

Keyphrases

• Gene Expression 100%
• Receptor Gene 100%
• Phorbol 12-myristate 13-acetate 100%
• Phorbol Ester 100%
• Human Platelets 100%
• Thromboxane Receptor 100%
• Transcription Start Site 25%
• K562 Cells 25%
• Megakaryocytic Differentiation 25%
• Protein Level 12%
• MRNA Level 12%
• Platelets 12%
• Gene Promoter 12%
• Nuclear Proteins 12%
• Promoter Region 12%
• Receptor Expression 12%
• DNA Segment 12%
• Inverted Repeats 12%
• Reporter Construct 12%
• Gel Shift Assay 12%
• Responsive Element 12%
• Circ 12%
• Stem-loop 12%
• Response Element 12%
• Responsive Genes 12%
• K562 12%
• GC Box 12%
• Kinase Activity Reporter 12%
• Loop Conformation 12%
• Sp1 Binding Site 12%
• Level Control 12%
• Sp1 Protein 12%

Biochemistry, Genetics and Molecular Biology

• Gene Expression 100%
• Receptor Gene 100%
• Myristic Acid 100%
• Thromboxane Receptor 100%
• Platelet 100%
• Upregulation 25%
• Transcription Initiation Site 25%
• K562 Cells 25%
• Messenger RNA 25%
• Enhancer Region 12%
• Binding Site 12%
• Kinase 12%
• Phosphotransferase 12%
• Promoter Region 12%
• Conformation 12%
• Gene Promoter 12%
• Nuclear Protein 12%
• Electrophoretic Mobility Shift Assay 12%
• Inverted Repeat 12%
• Response Element 12%
• Thymidine Monophosphate 12%
• GC Box 12%
• Stem-Loop 12%

Pharmacology, Toxicology and Pharmaceutical Science

• 12-O-Tetradecanoylphorbol-13-Acetate 100%
• Phorbol Ester 100%
• Thromboxane Receptor 100%
• Messenger RNA 25%
• Phosphotransferase 12%
• Binding Site 12%
• Nuclear Protein 12%
• Electrophoretic Mobility Shift Assay 12%
• Thymidine Phosphate 12%
• Pregnancy Specific Beta1 Glycoprotein 12%