Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists

Guo Hua Chu; Minghua Gu; Joel A. Cassel; Serge Belanger; Gabriel J. Stabley; Robert N. DeHaven; Nathalie Conway-James; Mike Koblish; Patrick J. Little; Diane L. DeHaven-Hudkins; Roland E. Dolle

doi:10.1016/j.bmcl.2005.10.034

Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists

Guo Hua Chu
, Minghua Gu
, Joel A. Cassel
, Serge Belanger
, Gabriel J. Stabley
, Robert N. DeHaven
, Nathalie Conway-James
, Mike Koblish
, Patrick J. Little
, Diane L. DeHaven-Hudkins
, Roland E. Dolle

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective κ opioid receptor agonists.

Original language	English
Pages (from-to)	645-648
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	16
Issue number	3
DOIs	https://doi.org/10.1016/j.bmcl.2005.10.034
State	Published - Feb 1 2006

Keywords

Analgesic
κ Opioid-receptor agonists

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10.1016/j.bmcl.2005.10.034

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title = "Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists",

abstract = "A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective κ opioid receptor agonists.",

keywords = "Analgesic, κ Opioid-receptor agonists",

author = "Chu, \{Guo Hua\} and Minghua Gu and Cassel, \{Joel A.\} and Serge Belanger and Stabley, \{Gabriel J.\} and DeHaven, \{Robert N.\} and Nathalie Conway-James and Mike Koblish and Little, \{Patrick J.\} and DeHaven-Hudkins, \{Diane L.\} and Dolle, \{Roland E.\}",

year = "2006",

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doi = "10.1016/j.bmcl.2005.10.034",

language = "English",

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journal = "Bioorganic and Medicinal Chemistry Letters",

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AU - Chu, Guo Hua

AU - Gu, Minghua

AU - Cassel, Joel A.

AU - Belanger, Serge

AU - Stabley, Gabriel J.

AU - DeHaven, Robert N.

AU - Conway-James, Nathalie

AU - Koblish, Mike

AU - Little, Patrick J.

AU - DeHaven-Hudkins, Diane L.

AU - Dolle, Roland E.

PY - 2006/2/1

Y1 - 2006/2/1

N2 - A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective κ opioid receptor agonists.

AB - A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective κ opioid receptor agonists.

KW - Analgesic

KW - κ Opioid-receptor agonists

UR - https://www.scopus.com/pages/publications/29544437967

U2 - 10.1016/j.bmcl.2005.10.034

DO - 10.1016/j.bmcl.2005.10.034

M3 - Article

C2 - 16263278

AN - SCOPUS:29544437967

SN - 0960-894X

VL - 16

SP - 645

EP - 648

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 3

ER -

Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists

Abstract

Keywords

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