Novel mutations target distinct subgroups of medulloblastoma

Giles Robinson; Matthew Parker; Tanya A. Kranenburg; Charles Lu; Xiang Chen; Li Ding; Timothy N. Phoenix; Erin Hedlund; Lei Wei; Xiaoyan Zhu; Nader Chalhoub; Suzanne J. Baker; Robert Huether; Richard Kriwacki; Natasha Curley; Radhika Thiruvenkatam; Jianmin Wang; Gang Wu; Michael Rusch; Xin Hong; Jared Becksfort; Pankaj Gupta; Jing Ma; John Easton; Bhavin Vadodaria; Arzu Onar-Thomas; Tong Lin; Shaoyi Li; Stanley Pounds; Steven Paugh; David Zhao; Daisuke Kawauchi; Martine F. Roussel; David Finkelstein; David W. Ellison; Ching C. Lau; Eric Bouffet; Tim Hassall; Sridharan Gururangan; Richard Cohn; Robert S. Fulton; Lucinda L. Fulton; David J. Dooling; Kerri Ochoa; Amar Gajjar; Elaine R. Mardis; Richard K. Wilson; James R. Downing; Jinghui Zhang; Richard J. Gilbertson

doi:10.1038/nature11213

Novel mutations target distinct subgroups of medulloblastoma

Giles Robinson, Matthew Parker, Tanya A. Kranenburg, Charles Lu, Xiang Chen, Li Ding, Timothy N. Phoenix, Erin Hedlund, Lei Wei, Xiaoyan Zhu, Nader Chalhoub, Suzanne J. Baker, Robert Huether, Richard Kriwacki, Natasha Curley, Radhika Thiruvenkatam, Jianmin Wang, Gang Wu, Michael Rusch, Xin HongJared Becksfort, Pankaj Gupta, Jing Ma, John Easton, Bhavin Vadodaria, Arzu Onar-Thomas, Tong Lin, Shaoyi Li, Stanley Pounds, Steven Paugh, David Zhao, Daisuke Kawauchi, Martine F. Roussel, David Finkelstein, David W. Ellison, Ching C. Lau, Eric Bouffet, Tim Hassall, Sridharan Gururangan, Richard Cohn, Robert S. Fulton, Lucinda L. Fulton, David J. Dooling, Kerri Ochoa, Amar Gajjar, Elaine R. Mardis, Richard K. Wilson, James R. Downing, Jinghui Zhang, Richard J. Gilbertson

Research output: Contribution to journal › Article › peer-review

690 Scopus citations

Original language	English
Pages (from-to)	43-48
Number of pages	6
Journal	Nature
Volume	488
Issue number	7409
DOIs	https://doi.org/10.1038/nature11213
State	Published - Aug 2 2012

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Robinson, G., Parker, M., Kranenburg, T. A., Lu, C., Chen, X., Ding, L., Phoenix, T. N., Hedlund, E., Wei, L., Zhu, X., Chalhoub, N., Baker, S. J., Huether, R., Kriwacki, R., Curley, N., Thiruvenkatam, R., Wang, J., Wu, G., Rusch, M., ... Gilbertson, R. J. (2012). Novel mutations target distinct subgroups of medulloblastoma. Nature, 488(7409), 43-48. https://doi.org/10.1038/nature11213

@article{ff1a9e3d60124a80934237087db6a6c4,

title = "Novel mutations target distinct subgroups of medulloblastoma",

author = "Giles Robinson and Matthew Parker and Kranenburg, {Tanya A.} and Charles Lu and Xiang Chen and Li Ding and Phoenix, {Timothy N.} and Erin Hedlund and Lei Wei and Xiaoyan Zhu and Nader Chalhoub and Baker, {Suzanne J.} and Robert Huether and Richard Kriwacki and Natasha Curley and Radhika Thiruvenkatam and Jianmin Wang and Gang Wu and Michael Rusch and Xin Hong and Jared Becksfort and Pankaj Gupta and Jing Ma and John Easton and Bhavin Vadodaria and Arzu Onar-Thomas and Tong Lin and Shaoyi Li and Stanley Pounds and Steven Paugh and David Zhao and Daisuke Kawauchi and Roussel, {Martine F.} and David Finkelstein and Ellison, {David W.} and Lau, {Ching C.} and Eric Bouffet and Tim Hassall and Sridharan Gururangan and Richard Cohn and Fulton, {Robert S.} and Fulton, {Lucinda L.} and Dooling, {David J.} and Kerri Ochoa and Amar Gajjar and Mardis, {Elaine R.} and Wilson, {Richard K.} and Downing, {James R.} and Jinghui Zhang and Gilbertson, {Richard J.}",

note = "Funding Information: Acknowledgements This research was supported as part of the St Jude Children{\textquoteright}s Research Hospital, Washington University Pediatric Cancer Genome Project. This work was supported by grants from the National Institutes of Health (R01CA129541, P01CA96832 and P30CA021765; R.J.G.), the Collaborative Ependymoma Research Network (CERN), Musicians against Childhood Cancer (MACC), The Noyes Brain Tumour Foundation, and by the American Lebanese Syrian Associated Charities (ALSAC).Weare grateful toS.Templefor the giftofreagents and the staffof the Hartwell Center for Bioinformatics and Biotechnology and ARC at St Jude Children{\textquoteright}s Research Hospital for technical assistance.",

year = "2012",

month = aug,

day = "2",

doi = "10.1038/nature11213",

language = "English",

volume = "488",

pages = "43--48",

journal = "Nature",

issn = "0028-0836",

number = "7409",

}

Robinson, G, Parker, M, Kranenburg, TA, Lu, C, Chen, X, Ding, L, Phoenix, TN, Hedlund, E, Wei, L, Zhu, X, Chalhoub, N, Baker, SJ, Huether, R, Kriwacki, R, Curley, N, Thiruvenkatam, R, Wang, J, Wu, G, Rusch, M, Hong, X, Becksfort, J, Gupta, P, Ma, J, Easton, J, Vadodaria, B, Onar-Thomas, A, Lin, T, Li, S, Pounds, S, Paugh, S, Zhao, D, Kawauchi, D, Roussel, MF, Finkelstein, D, Ellison, DW, Lau, CC, Bouffet, E, Hassall, T, Gururangan, S, Cohn, R, Fulton, RS , Fulton, LL, Dooling, DJ, Ochoa, K, Gajjar, A, Mardis, ER, Wilson, RK, Downing, JR, Zhang, J & Gilbertson, RJ 2012, 'Novel mutations target distinct subgroups of medulloblastoma', Nature, vol. 488, no. 7409, pp. 43-48. https://doi.org/10.1038/nature11213

TY - JOUR

T1 - Novel mutations target distinct subgroups of medulloblastoma

AU - Robinson, Giles

AU - Parker, Matthew

AU - Kranenburg, Tanya A.

AU - Lu, Charles

AU - Chen, Xiang

AU - Ding, Li

AU - Phoenix, Timothy N.

AU - Hedlund, Erin

AU - Wei, Lei

AU - Zhu, Xiaoyan

AU - Chalhoub, Nader

AU - Baker, Suzanne J.

AU - Huether, Robert

AU - Kriwacki, Richard

AU - Curley, Natasha

AU - Thiruvenkatam, Radhika

AU - Wang, Jianmin

AU - Wu, Gang

AU - Rusch, Michael

AU - Hong, Xin

AU - Becksfort, Jared

AU - Gupta, Pankaj

AU - Ma, Jing

AU - Easton, John

AU - Vadodaria, Bhavin

AU - Onar-Thomas, Arzu

AU - Lin, Tong

AU - Li, Shaoyi

AU - Pounds, Stanley

AU - Paugh, Steven

AU - Zhao, David

AU - Kawauchi, Daisuke

AU - Roussel, Martine F.

AU - Finkelstein, David

AU - Ellison, David W.

AU - Lau, Ching C.

AU - Bouffet, Eric

AU - Hassall, Tim

AU - Gururangan, Sridharan

AU - Cohn, Richard

AU - Fulton, Robert S.

AU - Fulton, Lucinda L.

AU - Dooling, David J.

AU - Ochoa, Kerri

AU - Gajjar, Amar

AU - Mardis, Elaine R.

AU - Wilson, Richard K.

AU - Downing, James R.

AU - Zhang, Jinghui

AU - Gilbertson, Richard J.

N1 - Funding Information: Acknowledgements This research was supported as part of the St Jude Children’s Research Hospital, Washington University Pediatric Cancer Genome Project. This work was supported by grants from the National Institutes of Health (R01CA129541, P01CA96832 and P30CA021765; R.J.G.), the Collaborative Ependymoma Research Network (CERN), Musicians against Childhood Cancer (MACC), The Noyes Brain Tumour Foundation, and by the American Lebanese Syrian Associated Charities (ALSAC).Weare grateful toS.Templefor the giftofreagents and the staffof the Hartwell Center for Bioinformatics and Biotechnology and ARC at St Jude Children’s Research Hospital for technical assistance.

PY - 2012/8/2

Y1 - 2012/8/2

UR - http://www.scopus.com/inward/record.url?scp=84864444165&partnerID=8YFLogxK

U2 - 10.1038/nature11213

DO - 10.1038/nature11213

M3 - Article

C2 - 22722829

AN - SCOPUS:84864444165

SN - 0028-0836

VL - 488

SP - 43

EP - 48

JO - Nature

JF - Nature

IS - 7409

ER -

Novel mutations target distinct subgroups of medulloblastoma

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