Novel Hexakis(areneisonitrile)technetium(I) Complexes as Radioligands Targeted to the Multidrug Resistance P-Glycoprotein

Keyphrases

• Amines 16%
• Aromatics 16%
• Aryl 16%
• Blood-brain Barrier 16%
• Cationic Compounds 16%
• Cellular Accumulation 33%
• Chinese Hamster Lung Fibroblast 16%
• Dichlorocarbene 16%
• Expression Pattern 16%
• Functional Imaging 16%
• Functional Modulation 16%
• Hepatobiliary Excretion 16%
• Human Tissue 16%
• Image Properties 16%
• Isonitrile 33%
• Lipophilic 33%
• Lipophilicity 16%
• Monocationic 16%
• Most Complex 16%
• Multidrug Resistance 100%
• Multidrug Resistance Protein 1 (MDR1) 16%
• Non-carriers 16%
• Organometallic Complexes 16%
• P-glycoprotein (P-gp) 100%
• P-glycoprotein Expression 16%
• P-glycoprotein Inhibitor 16%
• Pertechnetate 16%
• Phase Transfer 16%
• Physiological Expression 16%
• Radioligand 100%
• Renal Excretion 16%
• Sodium Dithionite 16%
• Substituted Aromatics 16%
• Technetium 100%
• Technetium-99m 16%
• Verapamil 16%
• Whole-body Biodistribution 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Biodistribution 12%
• Blood-Brain Barrier 12%
• Chinese Hamster 12%
• Leporidae 12%
• Lipophilicity 12%
• Multidrug Resistance 100%
• Multidrug Resistance Protein 1 12%
• P-Glycoprotein 100%
• Pertechnetate 12%
• Radioligand 100%
• Renal Excretion 12%
• Sodium Dithionite 12%
• Technetium 100%
• Technetium 99m 12%
• Verapamil 12%

Chemistry

• Dichlorocarbene 12%
• Glycoprotein 100%
• Lipophilicity 12%
• Multiple Drug Resistance 100%
• Organometallic Complexes 12%
• Radioligand 100%
• Sodium Dithionite 12%
• Technetium 100%
• Verapamil 12%