Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection: The Utility of18F-FDG PET Imaging

Zaid N. Safiullah; Jacqueline M. Latina; Efthymios Ziogos; Tarek Harb; Thomas H. Schindler; Ines Valenta-Schindler; Abass Alavi; Gary Gerstenblith; Thorsten M. Leucker

doi:10.1097/RLU.0000000000004762

Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection: The Utility of¹⁸F-FDG PET Imaging

Zaid N. Safiullah, Jacqueline M. Latina, Efthymios Ziogos, Tarek Harb, Thomas H. Schindler, Ines Valenta-Schindler, Abass Alavi, Gary Gerstenblith, Thorsten M. Leucker

Division of Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Spontaneous coronary artery dissection (SCAD) is an underdiagnosed etiology of acute coronary syndrome in women. Accurate diagnosis remains challenging but is imperative for treatment and prevention. We show here the utility of 18F-FDG PET imaging in SCAD diagnosis. We present 1 representative case of 4 women with suspected SCAD on coronary angiography from the EVACS (Evolocumab in Acute Coronary Syndromes) clinical trial. 18F-FDG PET imaging showed acute inflammation in the distribution of the suspected dissected coronary artery identified on angiography. Localized myocardial inflammation identified on 18F-FDG PET imaging can aid in diagnosing SCAD suspected on coronary angiography.

Original language	English
Pages (from-to)	802-803
Number of pages	2
Journal	Clinical nuclear medicine
Volume	48
Issue number	9
DOIs	https://doi.org/10.1097/RLU.0000000000004762
State	Published - Sep 1 2023

Keywords

PET
SCAD
cardiovascular imaging

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10.1097/RLU.0000000000004762

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title = "Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection: The Utility of18F-FDG PET Imaging",

abstract = "Spontaneous coronary artery dissection (SCAD) is an underdiagnosed etiology of acute coronary syndrome in women. Accurate diagnosis remains challenging but is imperative for treatment and prevention. We show here the utility of 18F-FDG PET imaging in SCAD diagnosis. We present 1 representative case of 4 women with suspected SCAD on coronary angiography from the EVACS (Evolocumab in Acute Coronary Syndromes) clinical trial. 18F-FDG PET imaging showed acute inflammation in the distribution of the suspected dissected coronary artery identified on angiography. Localized myocardial inflammation identified on 18F-FDG PET imaging can aid in diagnosing SCAD suspected on coronary angiography.",

keywords = "PET, SCAD, cardiovascular imaging",

author = "Safiullah, {Zaid N.} and Latina, {Jacqueline M.} and Efthymios Ziogos and Tarek Harb and Schindler, {Thomas H.} and Ines Valenta-Schindler and Abass Alavi and Gary Gerstenblith and Leucker, {Thorsten M.}",

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doi = "10.1097/RLU.0000000000004762",

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T1 - Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection

T2 - The Utility of18F-FDG PET Imaging

AU - Safiullah, Zaid N.

AU - Latina, Jacqueline M.

AU - Ziogos, Efthymios

AU - Harb, Tarek

AU - Schindler, Thomas H.

AU - Valenta-Schindler, Ines

AU - Alavi, Abass

AU - Gerstenblith, Gary

AU - Leucker, Thorsten M.

PY - 2023/9/1

Y1 - 2023/9/1

N2 - Spontaneous coronary artery dissection (SCAD) is an underdiagnosed etiology of acute coronary syndrome in women. Accurate diagnosis remains challenging but is imperative for treatment and prevention. We show here the utility of 18F-FDG PET imaging in SCAD diagnosis. We present 1 representative case of 4 women with suspected SCAD on coronary angiography from the EVACS (Evolocumab in Acute Coronary Syndromes) clinical trial. 18F-FDG PET imaging showed acute inflammation in the distribution of the suspected dissected coronary artery identified on angiography. Localized myocardial inflammation identified on 18F-FDG PET imaging can aid in diagnosing SCAD suspected on coronary angiography.

AB - Spontaneous coronary artery dissection (SCAD) is an underdiagnosed etiology of acute coronary syndrome in women. Accurate diagnosis remains challenging but is imperative for treatment and prevention. We show here the utility of 18F-FDG PET imaging in SCAD diagnosis. We present 1 representative case of 4 women with suspected SCAD on coronary angiography from the EVACS (Evolocumab in Acute Coronary Syndromes) clinical trial. 18F-FDG PET imaging showed acute inflammation in the distribution of the suspected dissected coronary artery identified on angiography. Localized myocardial inflammation identified on 18F-FDG PET imaging can aid in diagnosing SCAD suspected on coronary angiography.

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KW - SCAD

KW - cardiovascular imaging

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Novel Diagnostic Imaging Approach for Patients With Spontaneous Coronary Artery Dissection: The Utility of¹⁸F-FDG PET Imaging

Abstract

Keywords

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