@article{fb2f946fd26d4797aae3360dd7eba982,
title = "Novel and potent anti-malarial agents",
abstract = "Readily accessible, novel, and potent anti-malarial compounds have been developed. Optimization of the initial lead structure resulted in derivatives with IC50 values from 7 to 35 nM against chloroquine-sensitive and 70-350 nM against chloroquine-resistant strains of Plasmodium falciparum.",
author = "Brinner, {Kristin M.} and {Mi Kim}, Jin and Hiromu Habashita and Gluzman, {Ilya Y.} and Goldberg, {Daniel E.} and Ellman, {Jonathan A.}",
note = "Funding Information: We gratefully acknowledge the support of the Medicines for Malaria Venture and the Burroughs Wellcome Foundation. The Center for New Directions in Organic Synthesis is supported by Bristol-Myers Squibb as Sponsoring Member. ",
year = "2002",
month = nov,
doi = "10.1016/S0968-0896(02)00207-9",
language = "English",
volume = "10",
pages = "3649--3661",
journal = "Bioorganic and Medicinal Chemistry",
issn = "0968-0896",
number = "11",
}