Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment Study

John L. Keltner, Chris A. Johnson, Richard A. Levine, Juanjuan Fan, Kimberly E. Cello, Michael A. Kass, Mae O. Gordon

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Objective: To compare the occurrence of normal visual field (VF) test results following 2 vs 3 consecutive, abnormal, reliable test results in the Ocular Hypertension Treatment Study. Methods: The Ocular Hypertension Treatment Study is a prospective, multicenter follow-up study as part of a longitudinal randomized clinical trial. Sixty-four (68 eyes) of 1636 participants developed a VF primary open-angle glaucoma (POAG) end point. We compared the proportion of normal VF test results after a VF POAG end point among eyes whose VF abnormality was confirmed by 2 (n=9 eyes) vs 3 (n=59 eyes) consecutive, abnormal, reliable VF test results. Results: The proportion of VF test results that were normal subsequent to a VF POAG end point in eyes whose abnormality was confirmed by 2 consecutive, abnormal, reliable test results was significantly higher (73 [66%] of 110) compared with eyes whose abnormality was confirmed by 3 consecutive, abnormal, reliable test results (46 [12%] of 381) (P=.01). Conclusions: A VF POAG end point confirmed by 3 consecutive, abnormal, reliable VF test results appears to have greater specificity and stability than either 1 or 2 consecutive, abnormal, reliable VF test results. However, some eyes whose VF POAG end point was confirmed by 3 consecutive, abnormal, reliable test results nonetheless had 1 or more normal test results on follow-up.

Original languageEnglish
Pages (from-to)1201-1206
Number of pages6
JournalArchives of Ophthalmology
Volume123
Issue number9
DOIs
StatePublished - Sep 2005

Fingerprint Dive into the research topics of 'Normal visual field test results following glaucomatous visual field end points in the Ocular Hypertension Treatment Study'. Together they form a unique fingerprint.

Cite this