Normal Values of Left Ventricular Systolic and Diastolic Function Derived from Signal-averaged Acoustic Quantification Waveforms: A Multicenter Study

Kirk T. Spencer, Victor Mor-Avi, Jim Kirkpatrick, John Gorcsan, Thomas R. Kimball, Mark J. Monaghan, Julio E. Perez, Lynn Weinert, James Bednarz, Kathy Edelman, Betty Glascock, Jane Hancock, Chris Baumann, Roberto M. Lang

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Automated border-detection techniques such as acoustic quantification have proven accurate and useful for quantifying left ventricular (LV) function. We acquired LV acoustic quantification waveforms from the parasternal short-axis window in 140 healthy patients in the age range of 16 to 78 years. Signal-averaged waveforms were analyzed for parameters of systolic and diastolic performance. The average fractional area change was 54 ± 12%, and there were no significant changes in LV systolic function in the age range studied. There were significant changes in diastolic parameters with aging. The percentage of contribution to total LV filling occurring during atrial filling nearly tripled during the 6 decades studied, from 13% in the youngest cohort to 36% in the eighth decade of life. This study provides normal reference values for systolic and diastolic parameters of LV function determined from signal-averaged acoustic quantification waveforms acquired from the parasternal short-axis view in adult and adolescent patients over a wide age range.

Original languageEnglish
Pages (from-to)1244-1251
Number of pages8
JournalJournal of the American Society of Echocardiography
Volume16
Issue number12
DOIs
StatePublished - Dec 2003

Fingerprint Dive into the research topics of 'Normal Values of Left Ventricular Systolic and Diastolic Function Derived from Signal-averaged Acoustic Quantification Waveforms: A Multicenter Study'. Together they form a unique fingerprint.

  • Cite this

    Spencer, K. T., Mor-Avi, V., Kirkpatrick, J., Gorcsan, J., Kimball, T. R., Monaghan, M. J., Perez, J. E., Weinert, L., Bednarz, J., Edelman, K., Glascock, B., Hancock, J., Baumann, C., & Lang, R. M. (2003). Normal Values of Left Ventricular Systolic and Diastolic Function Derived from Signal-averaged Acoustic Quantification Waveforms: A Multicenter Study. Journal of the American Society of Echocardiography, 16(12), 1244-1251. https://doi.org/10.1067/j.echo.2003.09.002