Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines

Gregory J. Riely; Douglas E. Wood; Dara L. Aisner; Billy W. Loo; Andrea L. Axtell; Jessica R. Bauman; Ankit Bharat; Joe Y. Chang; Aakash Desai; Thomas J. Dilling; Jonathan Dowell; Gregory A. Durm; Scott Gettinger; Travis E. Grotz; Matthew A. Gubens; Aditya Juloori; Rudy P. Lackner; Michael Lanuti; Benjamin Levy; Jules Lin; Christine M. Lovly; Fabien Maldonado; Daniel Morgensztern; Trey C. Mullikin; Thomas Ng; Dawn Owen; Dwight H. Owen; Sandip P. Patel; Tejas Patil; Patricio M. Polanco; Jonathan Riess; Ana Lucia Ruano Mendez; Theresa A. Shapiro; Aditi P. Singh; James Stevenson; Alda Tam; Tawee Tanvetyanon; Jane Yanagawa; Edwin Yau; Kristina Gregory; Lisa Hang

doi:10.6004/jnccn.2025.0043

Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines

Gregory J. Riely
, Douglas E. Wood
, Dara L. Aisner
, Billy W. Loo
, Andrea L. Axtell
, Jessica R. Bauman
, Ankit Bharat
, Joe Y. Chang
, Aakash Desai
, Thomas J. Dilling
, Jonathan Dowell
, Gregory A. Durm
, Scott Gettinger
, Travis E. Grotz
, Matthew A. Gubens
, Aditya Juloori
, Rudy P. Lackner
, Michael Lanuti
, Benjamin Levy
, Jules Lin

Christine M. Lovly, Fabien Maldonado, Daniel Morgensztern, Trey C. Mullikin, Thomas Ng, Dawn Owen, Dwight H. Owen, Sandip P. Patel, Tejas Patil, Patricio M. Polanco, Jonathan Riess, Ana Lucia Ruano Mendez, Theresa A. Shapiro, Aditi P. Singh, James Stevenson, Alda Tam, Tawee Tanvetyanon, Jane Yanagawa, Edwin Yau, Kristina Gregory, Lisa Hang

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of NSCLC. These NCCN Guidelines Insights discuss recent updates to the NCCN Guidelines, with a focus on systemic therapy options for the treatment of patients with nonmetastatic NSCLC and the corresponding molecular testing considerations.

Original language	English
Pages (from-to)	354-362
Number of pages	9
Journal	JNCCN Journal of the National Comprehensive Cancer Network
Volume	23
Issue number	9
DOIs	https://doi.org/10.6004/jnccn.2025.0043
State	Published - Sep 2025

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Riely, G. J., Wood, D. E., Aisner, D. L., Loo, B. W., Axtell, A. L., Bauman, J. R., Bharat, A., Chang, J. Y., Desai, A., Dilling, T. J., Dowell, J., Durm, G. A., Gettinger, S., Grotz, T. E., Gubens, M. A., Juloori, A., Lackner, R. P., Lanuti, M., Levy, B., ... Hang, L. (2025). Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines. JNCCN Journal of the National Comprehensive Cancer Network, 23(9), 354-362. https://doi.org/10.6004/jnccn.2025.0043

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title = "Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines",

abstract = "The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of NSCLC. These NCCN Guidelines Insights discuss recent updates to the NCCN Guidelines, with a focus on systemic therapy options for the treatment of patients with nonmetastatic NSCLC and the corresponding molecular testing considerations.",

author = "Riely, \{Gregory J.\} and Wood, \{Douglas E.\} and Aisner, \{Dara L.\} and Loo, \{Billy W.\} and Axtell, \{Andrea L.\} and Bauman, \{Jessica R.\} and Ankit Bharat and Chang, \{Joe Y.\} and Aakash Desai and Dilling, \{Thomas J.\} and Jonathan Dowell and Durm, \{Gregory A.\} and Scott Gettinger and Grotz, \{Travis E.\} and Gubens, \{Matthew A.\} and Aditya Juloori and Lackner, \{Rudy P.\} and Michael Lanuti and Benjamin Levy and Jules Lin and Lovly, \{Christine M.\} and Fabien Maldonado and Daniel Morgensztern and Mullikin, \{Trey C.\} and Thomas Ng and Dawn Owen and Owen, \{Dwight H.\} and Patel, \{Sandip P.\} and Tejas Patil and Polanco, \{Patricio M.\} and Jonathan Riess and Mendez, \{Ana Lucia Ruano\} and Shapiro, \{Theresa A.\} and Singh, \{Aditi P.\} and James Stevenson and Alda Tam and Tawee Tanvetyanon and Jane Yanagawa and Edwin Yau and Kristina Gregory and Lisa Hang",

note = "Publisher Copyright: {\textcopyright} JNCCN—Journal of the National Comprehensive Cancer Network.",

year = "2025",

month = sep,

doi = "10.6004/jnccn.2025.0043",

language = "English",

volume = "23",

pages = "354--362",

journal = "JNCCN Journal of the National Comprehensive Cancer Network",

issn = "1540-1405",

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Riely, GJ, Wood, DE, Aisner, DL, Loo, BW, Axtell, AL, Bauman, JR, Bharat, A, Chang, JY, Desai, A, Dilling, TJ, Dowell, J, Durm, GA, Gettinger, S, Grotz, TE, Gubens, MA, Juloori, A, Lackner, RP, Lanuti, M, Levy, B, Lin, J, Lovly, CM, Maldonado, F, Morgensztern, D, Mullikin, TC, Ng, T, Owen, D, Owen, DH, Patel, SP, Patil, T, Polanco, PM, Riess, J, Mendez, ALR, Shapiro, TA, Singh, AP, Stevenson, J, Tam, A, Tanvetyanon, T, Yanagawa, J, Yau, E, Gregory, K & Hang, L 2025, 'Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines', JNCCN Journal of the National Comprehensive Cancer Network, vol. 23, no. 9, pp. 354-362. https://doi.org/10.6004/jnccn.2025.0043

TY - JOUR

T1 - Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines

AU - Riely, Gregory J.

AU - Wood, Douglas E.

AU - Aisner, Dara L.

AU - Loo, Billy W.

AU - Axtell, Andrea L.

AU - Bauman, Jessica R.

AU - Bharat, Ankit

AU - Chang, Joe Y.

AU - Desai, Aakash

AU - Dilling, Thomas J.

AU - Dowell, Jonathan

AU - Durm, Gregory A.

AU - Gettinger, Scott

AU - Grotz, Travis E.

AU - Gubens, Matthew A.

AU - Juloori, Aditya

AU - Lackner, Rudy P.

AU - Lanuti, Michael

AU - Levy, Benjamin

AU - Lin, Jules

AU - Lovly, Christine M.

AU - Maldonado, Fabien

AU - Morgensztern, Daniel

AU - Mullikin, Trey C.

AU - Ng, Thomas

AU - Owen, Dawn

AU - Owen, Dwight H.

AU - Patel, Sandip P.

AU - Patil, Tejas

AU - Polanco, Patricio M.

AU - Riess, Jonathan

AU - Mendez, Ana Lucia Ruano

AU - Shapiro, Theresa A.

AU - Singh, Aditi P.

AU - Stevenson, James

AU - Tam, Alda

AU - Tanvetyanon, Tawee

AU - Yanagawa, Jane

AU - Yau, Edwin

AU - Gregory, Kristina

AU - Hang, Lisa

PY - 2025/9

Y1 - 2025/9

N2 - The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of NSCLC. These NCCN Guidelines Insights discuss recent updates to the NCCN Guidelines, with a focus on systemic therapy options for the treatment of patients with nonmetastatic NSCLC and the corresponding molecular testing considerations.

AB - The NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC) provide recommendations for the treatment of NSCLC. These NCCN Guidelines Insights discuss recent updates to the NCCN Guidelines, with a focus on systemic therapy options for the treatment of patients with nonmetastatic NSCLC and the corresponding molecular testing considerations.

UR - https://www.scopus.com/pages/publications/105015595962

U2 - 10.6004/jnccn.2025.0043

DO - 10.6004/jnccn.2025.0043

M3 - Article

C2 - 40930154

AN - SCOPUS:105015595962

SN - 1540-1405

VL - 23

SP - 354

EP - 362

JO - JNCCN Journal of the National Comprehensive Cancer Network

JF - JNCCN Journal of the National Comprehensive Cancer Network

IS - 9

ER -

Non–Small Cell Lung Cancer, Version 7.2025 Featured Updates to the NCCN Guidelines

Abstract

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